Amino Acids (Drugs) Flashcards
Glutamate
Excitatory Amino Acid in brain
Aspartate
Similar effect to Glutamate in brain
–> Excitatory Effect
GABA
Inhibitory Transmitter in brain
Glycine
Inhibitory neurotransmitter in spinal cord and brain stem
Ketamine
NMDA Receptor Blocker
–> Anaesthetic
Phencyclidine
NMDA Receptor Blocker
–> Psychomimetic
Memantine
NMDA Receptor Blocker
–> Alzheimer
Perampanel
AMPA Receptor Non-Competitive Antagonist
Treats –> Epilepsy
Alcohol
GABA(A) Agonist
Benzodiazapines
GABA(A) Agonist
Barbiturates
GABA(A) Agonist
Baclofen
GABA(B) Agonist
–> Treats Spasticity
Strychnine
Competitive Glycine Antagonist
–> Prevents Glycine Action
–> Convulsant Poison
Tetanus Toxin
Inhibits Glycine Release from Inhibitory Neurons
–> Prevents Glycine Action
–> Violent Muscle Spasms
Amphetamine
Inhibits transporters needed to reuptake dopamine
–> Increased dopamine in synapse