Amino Acids (Drugs) Flashcards

1
Q

Glutamate

A

Excitatory Amino Acid in brain

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2
Q

Aspartate

A

Similar effect to Glutamate in brain
–> Excitatory Effect

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3
Q

GABA

A

Inhibitory Transmitter in brain

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4
Q

Glycine

A

Inhibitory neurotransmitter in spinal cord and brain stem

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5
Q

Ketamine

A

NMDA Receptor Blocker
–> Anaesthetic

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6
Q

Phencyclidine

A

NMDA Receptor Blocker
–> Psychomimetic

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7
Q

Memantine

A

NMDA Receptor Blocker
–> Alzheimer

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8
Q

Perampanel

A

AMPA Receptor Non-Competitive Antagonist
Treats –> Epilepsy

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9
Q

Alcohol

A

GABA(A) Agonist

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10
Q

Benzodiazapines

A

GABA(A) Agonist

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11
Q

Barbiturates

A

GABA(A) Agonist

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12
Q

Baclofen

A

GABA(B) Agonist
–> Treats Spasticity

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13
Q

Strychnine

A

Competitive Glycine Antagonist
–> Prevents Glycine Action
–> Convulsant Poison

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14
Q

Tetanus Toxin

A

Inhibits Glycine Release from Inhibitory Neurons
–> Prevents Glycine Action
–> Violent Muscle Spasms

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15
Q

Amphetamine

A

Inhibits transporters needed to reuptake dopamine
–> Increased dopamine in synapse

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16
Q

Cocaine

A

Inhibits transporters needed to reuptake dopamine
–> Increased dopamine in synapse