Anti-Platlet (General)

Question 1

Hemostasis Process

Answer 1

1. Vascular Injury
2. Platelet Adhesion
3. Platelet Aggregation
4. Coagulation
5. Fibrinolysis
6. Vascular Repair

Question 2

Platelet Signalling

Answer 2

1. Platelet Activation
2. Platelet Release
3. ADP or TXA2 activates GPIIB or IIIA
4. Fibrinogen Binding
5. Aggregation

Question 3

White Clots
- Location
- Composition
- Risk Factor
- Treatment

Answer 3

Arteries of Heart and Brain

Contains platelets and some fibrin

Ruptured artheroschlerotic plaque

Anti-platelet drugs

Question 4

Red Clots
- Location
- Composition
- Risk Factor
- Treatment

Answer 4

Veins, chambers of the heart

Fibrin and Erythrocytes

Slow/Disturbed blood flow

• Anticoagulant drugs

Question 5

Type 1 Myocardial Infarction

Answer 5

Thrombus is partially or fully occluding the artery, Artheriosclerotic plaque rupture
- Treat with antiplatelets

Question 6

Type 2 Myocardial Infarction

Answer 6

Non thrombolytic plaque
- Causes a imbalance in supply and demand of oxygen

Question 7

Treatment for Peripheral Artery Disease

Answer 7

ACEI
Statins
Anti-Platlet drugs

Question 8

Preventions of Thrombosis

Answer 8

Anti-Platelet Drugs
Anticoagulants

Question 9

Treatments of Thrombosis

Answer 9

Thrombolytic Drugs
(Fibrinolytics)

Question 10

Anti-platelet Drugs Goal

Answer 10

Prevent platelets from aggregating (sticking together)
- Prevents adverse cardiovascular events such as myocardial infarction/stroke