Protazoa

Question 1

Pt presents with megacolon, megaesophogus, achalasia with unilateral peri-orbital swelling. What additional clinical findings is likely to be found without intervention?

Answer 1

dilated cadiomyopathy with apical atrophy – Chagas disease from Trypaanosoma cruzi

Romana sign, deduviid bug

Question 2

what is treatment for Chagas/T. cruzi infection?

Answer 2

benzidazole or nifurtimox

Question 3

how is Chagas diagnosed?

Answer 3

trypomastigote seen on peripheral blood smear - looks like a weird dark pink cresentric sea-horse

Question 4

what is the transmission source of leshmania donovani?

Answer 4

sandfly

Question 5

how is leshmaniasis diagnosed?

Answer 5

presents clinically with spiking fevers, hepatospelnomegally, and pancytopenia

biopsy shows macrophages containing amastigoes (many little dark spots in cytoplasm

Question 6

how is leshmaniasis treated?

Answer 6

amphotericin B or sodium stibogluconate

Question 7

what is the cause of sexually transmitted, foul smelling greenish vaginal discharge that causes itching and burning pain

Answer 7

Trichomonas vaginalis - causes vaginitis

NOT vaginosis, which is caused by gardnerella vaginalis, non-painful, grey discharge with fishy smell

Question 8

what is the treatment for vaginitis?

Answer 8

metronidazole for patient AND partner

Question 9

how is Trichomonas vaginalis infection diagnosed?

Answer 9

motile trophozoites seen on wet mount; clinically presents as “strawberry cervix”