chemical carcinogens Flashcards

1
Q
Aflatoxins
Vinyl chloride
Nitrosamines
Cigarette smoke
Asbestos
Arsenic
Naphthalene (aniline) dyes
Alkylating agents
A

Hepatocellular carcinoma

Angiosarcoma (of the liver)

Esophagus
Stomach
    Squamous cell carcinoma
        laryngeal
        lung
    Small cell carcinoma of the lung
    Renal cell carcinoma
    Transitional cell carcinoma
Mesothelioma
Bronchogenic carcinoma

Squamous cell carcinoma of the skin
Angiosarcoma of the liver

Transitional cell carcinoma

Leukemia
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2
Q

Aflatoxins

A

Hepatocellular carcinoma

Derived from Aspergillus contamination of stored grains
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3
Q

Vinyl chloride

A

Angiosarcoma (of the liver)

Chemical used in the production of PVC pipes
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4
Q

Nitrosamines

A

Esophagus
Stomach

Found in smoked food. High levels of consumption in Japan.
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5
Q

Cigarette smoke

A
Squamous cell carcinoma
        laryngeal
        lung
Small cell carcinoma of the lung
Renal cell carcinoma
Transitional cell carcinoma
Key carcinogens are polycyclic hydrocarbons
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6
Q

Asbestos

A

Mesothelioma
Bronchogenic carcinoma

Bronchogenic carcinoma is a more common sequelae of asbestos than mesothelioma
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7
Q

Arsenic

A

Squamous cell carcinoma of the skin
Angiosarcoma of the liver

Also found in cigarette smoke
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8
Q

Naphthalene (aniline) dyes

A

Transitional cell carcinoma

Also found in cigarette smoke
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9
Q

Alkylating agents

A

Leukemia

May result from chemotherapy
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