Adverse drug effects Flashcards
pt is treated with high-dose intravenous acyclovir. What are potential adverse effects? What would prevent this?
crystalline nephrotoxicity, seizures, confusion
Prevent with aggressive IV hydration
What would prevent radiocontrast-induced allergic reactions?
prednisone
HIV pt is treated with appropriate therapy and develops pancreatitis. What drug was responsible?
Didanosine (NRTI)
HIV pt is treated with appropriate therapy and develops dyslipodemia with insulin resistance. What drugs could have caused this?
stavudine efavirenz darunavir ritonavir abacavir lamivudine didanosine raltegravir nevirapine
protease inhibitors
ritonavir and darunavir
HIV pt is treated with appropriate therapy and develops myopathy. What drugs could have caused this?
stavudine efavirenz darunavir ritonavir abacavir lamivudine didanosine raltegravir nevirapine
integrase inhibitor
ralteGRAVir
doluteGRAVir
“muscles decay in GRAVes”
HIV pt is treated with appropriate therapy and develops myelosuppression and anemia. What drug caused this?
lamivudine
NRTI
what drug can cause hepatotoxicity and peripheral neuropathy due to cometition with vitamin B6 in neurotranmitter synthesis?
isoniazid
pregnant mother is accidentally treated with an ACE inhibitor. What is the likely consequence to the fetus?
abnormal kidney development