Adverse drug effects Flashcards

1
Q

pt is treated with high-dose intravenous acyclovir. What are potential adverse effects? What would prevent this?

A

crystalline nephrotoxicity, seizures, confusion

Prevent with aggressive IV hydration

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2
Q

What would prevent radiocontrast-induced allergic reactions?

A

prednisone

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3
Q

HIV pt is treated with appropriate therapy and develops pancreatitis. What drug was responsible?

A

Didanosine (NRTI)

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4
Q

HIV pt is treated with appropriate therapy and develops dyslipodemia with insulin resistance. What drugs could have caused this?

stavudine
efavirenz
darunavir
ritonavir
abacavir
lamivudine
didanosine
raltegravir
nevirapine
A

protease inhibitors

ritonavir and darunavir

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5
Q

HIV pt is treated with appropriate therapy and develops myopathy. What drugs could have caused this?

stavudine
efavirenz
darunavir
ritonavir
abacavir
lamivudine
didanosine
raltegravir
nevirapine
A

integrase inhibitor

ralteGRAVir
doluteGRAVir

“muscles decay in GRAVes”

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6
Q

HIV pt is treated with appropriate therapy and develops myelosuppression and anemia. What drug caused this?

A

lamivudine

NRTI

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7
Q

what drug can cause hepatotoxicity and peripheral neuropathy due to cometition with vitamin B6 in neurotranmitter synthesis?

A

isoniazid

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8
Q

pregnant mother is accidentally treated with an ACE inhibitor. What is the likely consequence to the fetus?

A

abnormal kidney development

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