GI and Pancreatic enzymes

Question 1

What is the function of VIP?

Answer 1

produced by pancreas
stimulates intestinal water secretion
counteracts gastrin in the stomach
promotes bicarb secretion from pancreas

Question 2

what stimulates gastrin release?

Answer 2

stomach distension,
peptides
vagal stimulation

Question 3

what is the target of secretin?

Answer 3

promotes bicarb secretion from pancreatic ductal epithelium - no effect on pancreatic enzyme secretion!

Question 4

what is the stimulus for somatostatin release?
What inibits its release?
What does it do?

Answer 4

low pH

vagal stimulation inhibits somatostatin release

somatostatin inhibits GH and TSH release, and also inhibits gastrin, CCK, VIP, secretin, insulin and glucagon