Population Genetics Flashcards
Population
A group of organisms of the same species occupying a particular area at a particular time and that can potentially interbreed
Population genetics
Study of genetics at the population level
Gene pool
All the alleles in a population
Allele frequency
Number of times a certain allele appears in the gene pool
Hardy Weinberg principle
Mathematical model that predicts allele frequencies for a particular gene will not change from generation to generation
Based on 5 assumptions
5 assumptions of Hardy Weinberg
No mutation of alleles
No selection in favour or against a given phenotype
Population large
No immigration or emigration occurs (genetic isolation)
Mating is at random
Mutations effect
Lead to creation of new alleles so changes the relative allele frequencies in a population of other alleles of the same gene
No selection effect
Selection for alleles: organisms with these favourable alleles more likely to survive reproduce and increase this allele frequency
Organisms with different alleles of same gene are more likely to die and reduce this allele frequency
Having a small population
More prone to genetic drift thus changes in allele frequency
Effect of migration/ immigration
Introduction of new alleles by immigration can reduce frequency of alleles of the same gene but increase this allele
And removal of alleles by emigration reduces allele frequency
Effect of selective mating
Individuals actively choosing mates with specific characteristics caused by specific alleles will alter allele frequency, as these individuals will reproduce more, to pass on these specific alleles to offspring
How are allele frequencies represented?
As decimals out of 1
Eg 0.8 = 80% of the gene pool has this allele
What do all the allele frequencies of one gene add up to?
1
Probability of an individual in a population having a certain allele is equal to…
The allele frequency of the total population
Hardy Weinberg equations
p + q = 1
p² + 2pq + q² = 1
What does p and q represent in the Hardy Weinberg equation?
p = one allele’s frequency
q = another allele (of the same gene)’s frequency
So p² and q² = frequency of homozygous for allele
pq = frequency of heterozygous, multiply by 2 because there’s 2 ways to achieve this = 2pq