Meiosis Flashcards
What is meiosis
A form of cell division which is required for sexual reproduction to produce 4 genetically varied and different haploid cells (gametes)
What cell begins meiosis?
A diploid cell (has homologous chromosomes)
What are homologous chromosomes?
A pair of chromosomes where one chromosome comes form the mother and the other from the father.
They have same genes but may be different alleles
What must the homologous chromosomes do before meiosis?
Replication: so each homologous chromosome is now composed of 2 genetically identical sister chromatids held together at the centromere
What do the homologous chromosomes do before meiosis 1?
Arrange themselves in the centre by homologous chromosome pair
And crossing over
Crossing over
Once the homologous chromosomes have paired up, crossing over of alleles occur where they overlap (to form chiasmata) and the non sister chromatids swap alleles
To form homologous chromosomes which have a unique combination of alleles
The product of crossing over
In each chromosomes, they now contain a unique combination of alleles
when the chromatids separate later on each daughter cell will be different and genetically varied
Because NONE of the chromatids are identical
What happens if crossing over doesn’t occur?
Then when the chromatids divide (that are genetically identical) so as a result decreases genetic variation of daughter cells, as they don’t have a unique combination of alleles
What happens during meiosis 1?
The homologous chromosomes are separated into 2 haploid daughter cells
This is varied by independent assortment
Independent assortment
When the homologous chromosomes are separating in meiosis 1, it is a random chance of which homologous chromosome will end up in which cell (because they have same genes but each have different alleles) eg which one will maternal or paternal go to?
So 4 daughter cells all have unique combination of maternal and paternal chromosomes
Meiosis 2
When the sister chromatids separate when the centromere divides
What does meiosis 2 produce?
4 haploid daughter cells that are genetically different from each other
How many possible combinations are there for maternal and paternal chromosomes in meiosis 1 (for what cell they are divided into)?
2^n
Where n is the number of homologous pairs eg 23 in a human
End of meiosis
Each haploids cell dna decondenses as it doesn’t need to be replicated
Sexual reproduction
The fusion of 2 gametes in fertilisation to produce a zygote.