Pharmacology - Intestinal Motility Flashcards

1
Q

name five types of anti-emetic drugs

A
antihistamines
antimuscarinics 
5-HT3 receptor antagonists 
dopamine receptor antagonists 
neurokinin-1 receptor antagonists
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2
Q

how do antihistamines work?

A

H1 receptor antagonists

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3
Q

what side effect of antihistamines is due to crossing the BBB?

A

sleepiness

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4
Q

name three antihistamines that can be used for nausea

A

cyclizine
promethazine
diphenhydramine

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5
Q

what type of anti-emetic is used specifically for motion sickness?

A

anti-muscarinics

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6
Q

name an anti-muscarinic anti emetic

A

scopolamine

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7
Q

name three 5-Ht3 receptor antagonists

A

ondansetron
granisetron
palonosetron

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8
Q

what are some possible side effects of 5-Ht3 receptor antagonists?

A

constipation
diarrhoea
headache

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9
Q

name some dopamine receptor antagonists

A
chlorpromazine
droperidol
haloperidol
prochlorperazine
metoclopramide
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10
Q

name two neurokinin 1 receptor antagonists

A

fosaprepitant

aprepitant

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11
Q

name two anti-diarrhoeal drugs

A

loperamide

diphenoxylate

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12
Q

name some possible side effects of anti-diarrhoeal drugs

A

constipation
sedation
respiratory depression

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13
Q

name a bulk forming laxative

A

ispaghula husk

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14
Q

name an osmotic laxative

A

lactulose

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15
Q

name a stimulant laxative

A

senna

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