Pathology - Stomach Flashcards
name some possible causes of acute gastritis
burns chemicals shock trauma head injury
name the three possible causes of chronic gastritis
autoimmune
bacterial
chemical
what autoantibodies are associated with autoimmune gastritis?
anti-parietal
anti intrinsic factor
what haematological complication can occur in autoimmune gastritis and why?
pernicious anaemia
due to B12 deficiency
what pathological changes can be seen in autoimmune gastritis?
atrophy and intestinal metaplasia in the body of the stomach
what is the most common cause of bacterial gastritis?
H.pylori
what does H.Pylori gastritis increase the risk of?
peptic ulcers
gastric cancers
name three possible causes of chemical gastritis
NSAIDs
alcohol
bile reflux
what is peptic ulceration?
a breach in the GI mucosa as a result of acid and pepsin attack
what parts of the GI tract can be affected by peptic ulcers?
1st part of the duodenum
stomach
gastro oesophageal junction
stomas
describe the overall appearance of peptic ulcers
2-10cm
edges are clear cut and punched out
what are some possible complications of peptic ulcers?
perforation
haemorrhage
stenosis
intractable pain