Pathology: Large Bowel Flashcards
what two things are often related to diverticular disease?
low fibre diet
increased intralumenal pressure
when are there symptoms in diverticular disease?
only if it becomes complicated
what is required in complicated diverticular disease?
surgery
name five possible complications of diverticular disease
inflammation rupture abscess fistula massive bleeding
what does an ischaemic bowel look like on histology?
withered crupts
smudged lamina propria
few chronic inflammatory cells
who is ischaemia of the large bowel common in?
the elderly
which side of the bowel is most commonly affected by ischaemia?
left
name six possible causes of ischaemia of the large bowel
CVD AF embolus atherosclerosis of mesenteric vessels shock vasculitis
name three possible complications of ischaemic of the large bowel
massive bleeding
rupture
stricture
what appears on the mucosal surface in Antibiotic Induced Pseudomembranous Colitis?
yellow, purulent exudate
what type of antibiotic causes antibiotic induced pseudomembranous colitis?
broad spectrum antibiotics
what attacks the endothelium and epithelium in antibiotic induced pseudomembranous colitis?
C.Diff toxins A and B
what does antibiotic induced pseudomembranous colitis cause?
massive diarrhoea and bleeding
how is antibiotic induced pseudomembranous colitis treated?
flagyl
vancomycin
colectomy
what is another name for flagyl?
metronidazole
