peds83 Flashcards
why would you give steroids with antibiotics to treat meningitis?
before or with first dose of abx; effectively reduce hearing loss in HIB meningitis
complications of meningitis
hearing loss is most common (up to 25% of patients); global brain injury occurs in 5-10%; SIADH, seizures, hydrocephalus; brain abscess, CN palsy; learning disability; and focal neuro defects
CSF in acute bacterial infection
high protein, low glucose
CSF in viral meningitis
normal to high protein, normal glucose
tuberculosis meningitis- CSF
lymphocytes predom (as opposed to PMNs in bacterial); very high protein; very low glucose
CSF in fungal meningitis
lymphocytes predom; normal to high protein; low glucose
CSF in parameningeal focus (brain abscess)
polys or monos predom; high protein; low glucose; CSF culture neg
aseptic meningitis
inflamm of the meninges with CSF lymphocyte pleocytosis; can be caused by virus (most common) or TB
classic finding on brain imaging for TB meningitis
basilar enhancement
acid fast stains in TB meningitis?
rarely positive
most common cause of aseptic meningitis
viral
most common cause of viral meningitis
enteroviruses, mumps, lymphocytic choriomeningitis, herpes viruses (EBV, CMV, VZV)
viruses that commonly cause encephalitis and meningitis together
arboviruses (St louis, Western equine, Eastern equine, west nile virus), influenza, herpes virus
bacterial causes of ASEPTIC meningitis
mycobacterim tuberculosis; borrelia burgdorferi (lyme dz); treponema pallidum(syphilis)
fungal causes of aseptic meningitis
coccidioides immitis, crypto, histoplasmosis