Pathology Part 6 Flashcards
Antibodies, B cells
Humoral immunity
Sensitized lymphocytes, T cells (thymus)
Cellular immunity
ACID hypersensitivity
Type 1: Allergy
Type 2: Cell-mediated
Type 3: Immune (SLE)
Type 4: Delayed (dermatitis)
Which type of hypersensitivity would myasthenia gravis fall under?
Type 2 (cell or Antibody mediated)
Which type of hypersensitivity would RA fall under?
Type 3 (autoImmune)
WBCs associated with acute bacterial infection
neutrophils
WBCs associated with viral infection or chronic disease
lymphocyte
WBCs associated with chronic infection
monocytes
WBCs associated with parasites and allergic reactions
eosinophils
parasites
IgE, Type 1 hypersensitivity, Eosinophils
similar to mast cells, make heparin and histamine
basophils
inability to produce antibodies due to lack of B cells
Bruton’s agammaglobulinemia
Bence Jones proteins
Multiple Myeloma
MC primary malignancy of the spine
Multiple myeloma
Retrovirus attacks T4 helper cells
AIDS
Kaposi’s sarcoma
AIDS
Parasitic pneumonia
AIDS
Autoimmune, MC hypoprathyroidism
Hashimoto’s
Starry sky appearance,
Epstein Barr virus
Burkitts Lymphoma
Blastic mets (prostate),
Paget’s,
Hodgkin’s
Ivory white vertebra
aka osteitis deformans
Paget’s Disease
Anemia present in all types
Leukemia
starry sky cells,
3-4 y/o,
leukemia
ALL (acute lympho….)
PHILADELPHIA chromosome,
MC 40-50 y/o,
leukemia
CML (Chronic myelocitic)
MC young adults,
aka acute granulocytic leukemia
AML (acute myeloblastic)
leukemia in the elderly
CLL (chronic lymphocytic)
Deficiency of proteins only, 50% of nursing home
Kwashiorkor (pot belly)
Deficiency of proteins an calories
Marasmus (wasting)
purulent
pus (mostly neutrophils)
free fluid in peritoneal cavity
ascites
exudate
no pitting edema (has proteins)
pitting edema, mostly albumin
transudate
protein mediator, activates and orchestrates inflammation response
cytokines