Pathology- Nervous system

Question 1

Owls eye appearance

Answer 1

Cytomegalovirus

Question 2

Negri bodies

Answer 2

Rabies

Question 3

Autosomal dominant neurodegeneration of caudate and putamen nuclei

Answer 3

Huntingtons disease- trinucleotide repeats

Chorea and dementia

Question 4

ALS

Answer 4

Motor neuron degeneration
UMNL and LMNL
Preserves extraocular muscles

Question 5

Neurological effects of B12 deficiency

Answer 5

PLS- glove and stocking paresthesia

Question 6

What disorder effects lateral spinothalamic tract

Answer 6

Syringomyelia- fluid filled cysts; loss of pain and temp

Question 7

Parkinson’s aka

Answer 7

Paralysis agitans

Question 8

Flame shaped bleeding in the pons dt transtentorial hemorrhage

Answer 8

Duret hemorrhage

Question 9

Arnold-Chiari malformation types

Answer 9

Type 1- adults, HA

type 2- kids CSF obstruction

Question 10

What does Arnold-chiari malformations affect?

Answer 10

Cerebellar tonsils herniating through foramen magnum

Question 11

What is a widespread white matter disruption, post-traumatic coma or death result

Answer 11

Diffuse axonal injury

Question 12

Intracranial arterial bleed

Answer 12

Epidural hematoma

Question 13

Intracranial venous bleed

Answer 13

Subdural hematoma

Question 14

Non progressive motor defects from perinatal CNS damage or anoxia

Answer 14

Cerebral palsy

Question 15

MS is an autoimmune demyelination of what? And what shows up on MRI?

Answer 15

CNS neurons

White matter plaques on MRI

Question 16

Which disorder causes Charcot’s triad, plaquing, staccato or slurred speech, tremors and nystagmus and more common in females

Answer 16

MS

Question 17

Polio can affect

Answer 17

Both CNS and PNS paralysis

Question 18

What is a benign nerve sheath tumor that is genetically inherited?

Answer 18

Neurofibroma

Question 19

Wet beriberi

Answer 19

Heart failure as well as dry sx

Question 20

Dry beriberi

Answer 20

Paresthesia, paralysis and nystagmus

Question 21

What is an autosomal dominant condition that causes benign tumors throughout the body and in CNS?

Answer 21

Tuberous sclerosis

Question 22

Horners syndrome

Answer 22

Sympathetics: ptosis, myosis, anhydrosis

Question 23

What is a pediatric brain tumor located in the cerebellum

Answer 23

Medulloblastoma

Question 24

Inherited peripheral neuropathy that produces pes caves

Answer 24

Charcot-Marie-tooth

Question 25

Neuromuscular junction disorder that involves autoimmune attack on pre-synaptic calcium ion channels?

Answer 25

Lambert-eaton

Question 26

Prolonged exposure to glucocorticoids may produce atrophy of?

Answer 26

Type II muscle fibers

Question 27

Elevated cortisol from steroid meds or adrenal adenoma

Answer 27

Cushings

Question 28

What are known as acoustic neuromas on CN VIII which can produce hearing loss

Answer 28

Schwannomas

Question 29

Which neurofibromatosis type has multiple cutaneous neurofibromas, Lisch nodules on iris and cafe au lait spots?

Answer 29

Type 1

Question 30

Which neurofibromatosis type has bilateral vestibular schwannomas with possible vision and hearing problems?

Answer 30

Type 2

Question 31

Malignant peripheral nerve sheath tumors are common in

Answer 31

Neurofibromatosis type 1

Question 32

Morton’s neuroma aka

Answer 32

Traumatic neuroma- disorganized Schwann cells common btw metatarsals, painful

Question 33

Which disease is hyperthyroidism and may damage muscle cells as a “thyroxic myopathy”?

Answer 33

Graves