Parvoviridae - General Characteristics

Question 1

What are the general properties of parvoviridae?

Answer 1

Non enveloped
Icosahedral
18-25 nm (small)
Virion capsin has 60 subunits
T = 1
Single stranded DNA genomes

Question 2

Where does replication occur?

Answer 2

Nucleus of actively dividing cells
Only cells that pass through mitotic S phase
Cannot replicate in stationary cells

Question 3

What are the two subfamilies?

Answer 3

Parvovirinae (vertebrae)

Densovirinae (insects)

Question 4

What are three diseases caused by parvoviridae family?

Answer 4

Feline Panleukopenia
Canine parvovirus
Porcine parvovirus

Question 5

What does genus Erythrovirus include?

Answer 5

Human parvovirus B19

Question 6

What are the common names for Erythrovirus?

Answer 6

Slap Cheek Rash

Fifth Disease

Question 7

What are the clinical signs of Slap Cheek Rash?

Answer 7

Mild rash called erythema infectious
Aplastic anemia
Painful joints

Question 8

Can Erythrovirus be passed from humans to dogs/cats or vice versa?

Answer 8

No!

Question 9

What is Genus Dependovirus?

Answer 9

Goose and duck parvo
Bovine parvovirus 2
Unable to replicate unless in the presence of a helper virus, usually an adenovirus.

Question 10

What is Genus Bocavirus?

Answer 10

Found in humans, dogs, cattle
Infect gastrointestinal and respiratory tract
Unique because they contain a third ORF (open reading fame) between non-structral and structural coding regions.