(Part 2) 2.25.1 Rickettsia and Related Organisms Flashcards by Miguel Acosta | Brainscape

Q

Rickettsia are Small, gram-negative, pleomorphic, fastidious and are obligate intracellular parasites.

T or F

A

T

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Q

Rickettsia multiply by binary fission in the Nucleus of the host cell

T or F

A

F

Not nucleus, cytoplasm

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Q

Humans are accidental host from the infection of Rickettsia

T or F

A

T

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Q

Rickettsia Triad includes Fever, Headache, and Vomiting

T or F

A

F

No vomiting, Rash

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Q

In microscopic exam of Ricketssia, using Giemsa stain is to detect?

a. Vorutille morulae
b. Ehrlichia morulae
c. Erythro morulae
d. Leuko morulae

A

b

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Q

What is the specimen used to detect Ehrlichia Morulae?

A

Buffy coat smear

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Q

Gold standard in detecting Rickettsia?

a. IFA
b. ELISA
c. DFA
d. PCR

A

a (Indirect immunofluorescence assay)

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Q

Based on cross reactivity of patient’s antibodies with polysaccharide

a. Weil-Felix reaction
b. Neufeld reaction
c. Gerald Reaction
d. Ox Reaction

A

a

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Q

Ox-19 strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

a

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Q

Ox-K strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

b

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Q

Ox-2 strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

a

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Q

Weil Felix test is sensitive and specific

T or F

A

F

Not sensitive and specific

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Q

What is the sample used in the Gold standard for Ricketssia?

A

Serum

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Q

What is the positive indicator for Weil-Felix test?

A

Agglutination

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Q

Mild illness

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

c

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Q

Rocky Mountain Spotted Fever

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

a

Q

Epidemic typhus, Brill-Zinsser disease

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

d

Q

Sennetsu fever

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

I

Q

Human monocytic ehrlichiosis

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

g

Q

Human granulocytic anaplasma

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

h

Q

Murine typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

e

Q

Scrub typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

f

Q

Mediterranean and Israeli spotted fever; Indain tick typhus; Kenya tick typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

b

Q

Which of the following Rickettsia has Tick (Dermacentor spp)

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi

A

a

Q

Which of the following has ticks as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

A

a and b

Q

Which of the following has Lice as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

A

c

Q

Which of the following has Fleas as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

A

d

Q

Which of the following has Chiggers as a vector?

a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu

A

a

Q

Which of the following has Chiggers as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

A

Q

Which of the following has Ticks as a vector?

a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu

A

b,c,d

Q

Causative agent of Q fever, an acute systemic infection that primarily affects lungs

a. Orientia tsutsugamushi
b. Coxiella burnetii
c. Anaplasma
d. Neorickettsia sennetsu

A

b

Q

MOT of C. burnetii

Inhalation of contaminated aerosols

T or F

A

T

Q

Coxiella is removed from Rickettsia and is now related to Legionella

T or F

A

T

Q

Most common reservoir for C. burnetii

A

Sheep, goat Cattle

Q

Lab diagnosis for C. burnetii includes:

PCR
IFa
EIA
Complement fixation

T or F

A

T

Q

Causative agent of Whipple Disease

A

Tropheryma Whipplei

Q

NOTE:

Tropheryma Whipplei is Characterized by the presence of Periodic Acid Shift (PAS)-staining macrophages in almost every organ system

The bacillus is observed in macrophages and affected tissue

A