(Part 2) 2.25.1 Rickettsia and Related Organisms Flashcards
Rickettsia are Small, gram-negative, pleomorphic, fastidious and are obligate intracellular parasites.
T or F
T
Rickettsia multiply by binary fission in the Nucleus of the host cell
T or F
F
Not nucleus, cytoplasm
Humans are accidental host from the infection of Rickettsia
T or F
T
Rickettsia Triad includes Fever, Headache, and Vomiting
T or F
F
No vomiting, Rash
In microscopic exam of Ricketssia, using Giemsa stain is to detect?
a. Vorutille morulae
b. Ehrlichia morulae
c. Erythro morulae
d. Leuko morulae
b
What is the specimen used to detect Ehrlichia Morulae?
Buffy coat smear
Gold standard in detecting Rickettsia?
a. IFA
b. ELISA
c. DFA
d. PCR
a (Indirect immunofluorescence assay)
Based on cross reactivity of patient’s antibodies with polysaccharide
a. Weil-Felix reaction
b. Neufeld reaction
c. Gerald Reaction
d. Ox Reaction
a
Ox-19 strain
a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii
a
Ox-K strain
a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii
b
Ox-2 strain
a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii
a
Weil Felix test is sensitive and specific
T or F
F
Not sensitive and specific
What is the sample used in the Gold standard for Ricketssia?
Serum
What is the positive indicator for Weil-Felix test?
Agglutination
Mild illness
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
c
Rocky Mountain Spotted Fever
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
a
Epidemic typhus, Brill-Zinsser disease
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
d
Sennetsu fever
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
I
Human monocytic ehrlichiosis
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
g
Human granulocytic anaplasma
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
h
Murine typhus
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
e
Scrub typhus
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
f
Mediterranean and Israeli spotted fever; Indain tick typhus; Kenya tick typhus
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu
b
Which of the following Rickettsia has Tick (Dermacentor spp)
a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
a
Which of the following has ticks as a vector?
a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi
a and b
Which of the following has Lice as a vector?
a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi
c
Which of the following has Fleas as a vector?
a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi
d
Which of the following has Chiggers as a vector?
a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu
a
Which of the following has Chiggers as a vector?
a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi
Which of the following has Ticks as a vector?
a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu
b,c,d
Causative agent of Q fever, an acute systemic infection that primarily affects lungs
a. Orientia tsutsugamushi
b. Coxiella burnetii
c. Anaplasma
d. Neorickettsia sennetsu
b
MOT of C. burnetii
Inhalation of contaminated aerosols
T or F
T
Coxiella is removed from Rickettsia and is now related to Legionella
T or F
T
Most common reservoir for C. burnetii
Sheep, goat Cattle
Lab diagnosis for C. burnetii includes:
PCR
IFa
EIA
Complement fixation
T or F
T
Causative agent of Whipple Disease
Tropheryma Whipplei
NOTE:
Tropheryma Whipplei is Characterized by the presence of Periodic Acid Shift (PAS)-staining macrophages in almost every organ system
- The bacillus is observed in macrophages and affected tissue
