(Part 2) 2.25.1 Rickettsia and Related Organisms Flashcards

1
Q

Rickettsia are Small, gram-negative, pleomorphic, fastidious and are obligate intracellular parasites.

T or F

A

T

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2
Q

Rickettsia multiply by binary fission in the Nucleus of the host cell

T or F

A

F

Not nucleus, cytoplasm

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3
Q

Humans are accidental host from the infection of Rickettsia

T or F

A

T

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4
Q

Rickettsia Triad includes Fever, Headache, and Vomiting

T or F

A

F

No vomiting, Rash

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5
Q

In microscopic exam of Ricketssia, using Giemsa stain is to detect?

a. Vorutille morulae
b. Ehrlichia morulae
c. Erythro morulae
d. Leuko morulae

A

b

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6
Q

What is the specimen used to detect Ehrlichia Morulae?

A

Buffy coat smear

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7
Q

Gold standard in detecting Rickettsia?

a. IFA
b. ELISA
c. DFA
d. PCR

A

a (Indirect immunofluorescence assay)

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8
Q

Based on cross reactivity of patient’s antibodies with polysaccharide

a. Weil-Felix reaction
b. Neufeld reaction
c. Gerald Reaction
d. Ox Reaction

A

a

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9
Q

Ox-19 strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

a

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10
Q

Ox-K strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

b

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11
Q

Ox-2 strain

a. Proteus vulgaris
b. Proteus mirabilis
c. Morganella morganii

A

a

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12
Q

Weil Felix test is sensitive and specific

T or F

A

F

Not sensitive and specific

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13
Q

What is the sample used in the Gold standard for Ricketssia?

A

Serum

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14
Q

What is the positive indicator for Weil-Felix test?

A

Agglutination

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15
Q

Mild illness

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

A

c

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16
Q

Rocky Mountain Spotted Fever

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

17
Q

Epidemic typhus, Brill-Zinsser disease

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

18
Q

Sennetsu fever

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

19
Q

Human monocytic ehrlichiosis

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

20
Q

Human granulocytic anaplasma

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

21
Q

Murine typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

22
Q

Scrub typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

23
Q

Mediterranean and Israeli spotted fever; Indain tick typhus; Kenya tick typhus

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi
f. Orientia tsutsugamushi
g. Ehrlichia chaffeensis
h. Anaplasma
I. Neorickettsia sennetsu

24
Q

Which of the following Rickettsia has Tick (Dermacentor spp)

a. R. ricekettsii
b. R. conorii
c. R. parkeri
d. R. prowazekii
e. R. typhi

25
Q

Which of the following has ticks as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

26
Q

Which of the following has Lice as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

27
Q

Which of the following has Fleas as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

28
Q

Which of the following has Chiggers as a vector?

a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu

29
Q

Which of the following has Chiggers as a vector?

a. R. conorii
b. R. parkeri
c. R. prowazekii
d. R. typhi

30
Q

Which of the following has Ticks as a vector?

a. Orientia tsutsugamushi
b. Ehrlichia chaffeensis
c. Anaplasma
d. Neorickettsia sennetsu

31
Q

Causative agent of Q fever, an acute systemic infection that primarily affects lungs

a. Orientia tsutsugamushi
b. Coxiella burnetii
c. Anaplasma
d. Neorickettsia sennetsu

32
Q

MOT of C. burnetii

Inhalation of contaminated aerosols

T or F

33
Q

Coxiella is removed from Rickettsia and is now related to Legionella

T or F

34
Q

Most common reservoir for C. burnetii

A

Sheep, goat Cattle

35
Q

Lab diagnosis for C. burnetii includes:

PCR
IFa
EIA
Complement fixation

T or F

36
Q

Causative agent of Whipple Disease

A

Tropheryma Whipplei

37
Q

NOTE:

Tropheryma Whipplei is Characterized by the presence of Periodic Acid Shift (PAS)-staining macrophages in almost every organ system

  • The bacillus is observed in macrophages and affected tissue