Parkinson's Disease Flashcards

1
Q

What is Parkinson’s Disease?

A

A progressive neurological disorder characterized by the degeneration of dopaminergic neurons in the Substantia Nigra, leading to altered motor function.

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2
Q

What neurotransmitter is primarily involved in movement in Parkinson’s Disease?

A

Dopamine.

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3
Q

What role does the Basal Ganglia play in Parkinson’s Disease?

A

It controls muscle tone and fine motor skills; dysfunction leads to various motor symptoms.

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4
Q

What is the function of the Striatum?

A

It is responsible for voluntary motor movement, learning, and behavior.

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5
Q

How does dopamine affect the Striatum?

A

Dopamine binds to D1 (excitatory) and D2 (inhibitory) receptors, affecting motor control.

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6
Q

What are the primary symptoms of Parkinson’s Disease?

A

Tremors, bradykinesia (slowness of movement), rigidity, and postural instability.

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7
Q

What causes the symptoms of Parkinson’s Disease?

A

Unbalanced signals due to reduced dopamine levels.

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8
Q

How often is medication typically administered for Parkinson’s Disease?

A

Every 2-4 hours.

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9
Q

What unique detection method was noted for Parkinson’s Disease?

A

A woman with a heightened sense of smell could detect changes in skin secretion (sebum) associated with Parkinson’s.

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10
Q

What are potential protective factors against Parkinson’s Disease?

A

Nicotine, caffeine, NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), omega-3 fatty acids, and hormone replacement therapy (HRT).

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