Parkinson's Disease Flashcards
What is Parkinson’s Disease?
A progressive neurological disorder characterized by the degeneration of dopaminergic neurons in the Substantia Nigra, leading to altered motor function.
What neurotransmitter is primarily involved in movement in Parkinson’s Disease?
Dopamine.
What role does the Basal Ganglia play in Parkinson’s Disease?
It controls muscle tone and fine motor skills; dysfunction leads to various motor symptoms.
What is the function of the Striatum?
It is responsible for voluntary motor movement, learning, and behavior.
How does dopamine affect the Striatum?
Dopamine binds to D1 (excitatory) and D2 (inhibitory) receptors, affecting motor control.
What are the primary symptoms of Parkinson’s Disease?
Tremors, bradykinesia (slowness of movement), rigidity, and postural instability.
What causes the symptoms of Parkinson’s Disease?
Unbalanced signals due to reduced dopamine levels.
How often is medication typically administered for Parkinson’s Disease?
Every 2-4 hours.
What unique detection method was noted for Parkinson’s Disease?
A woman with a heightened sense of smell could detect changes in skin secretion (sebum) associated with Parkinson’s.
What are potential protective factors against Parkinson’s Disease?
Nicotine, caffeine, NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), omega-3 fatty acids, and hormone replacement therapy (HRT).