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NYCC Histology > Pancreas > Flashcards

Pancreas Flashcards

1
Q

3 regions of pancreas

A

Head
Body
Tail

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2
Q

What divides the parenchyma of pancreas into lobules?

A

CT capsule extends septa (Trabeculae) of CT

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3
Q

Exocrine function of pancreas

A

Synthesize & secrete digestive enzymes into duodenum

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4
Q

Endocrine function of pancreas

A

Synthesize & secrete insulin & glucagon into blood (regulate glucose metabolism)

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5
Q

Islets of langerhans function

A

secrete hormones to regulate blood glucose levels

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6
Q

Islets of Langerhans have a rich network of ____

A

fenestrated capillaries

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7
Q

exocrine pancreas

Exocrine pancreas Secretory units are _____

A

Serous acini

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8
Q

exocrine pancreas

Serous acini are formed by…

A

A simple epithelium of pyramidal shaped cells

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9
Q

exocrine pancreas

exocrine pancreas Acinar cells are characterized by…

A

Distinct basophilia in basal cytoplasm and apical zymogen (secretory) granules

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10
Q

exocrine pancreas

Initial intercalated duct begins within the acinus with ____

A

Centroacinar cells

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11
Q

exocrine pancreas

Centroacinar cells & intercalated ducts secrete ____

A

Bicarbonate (HCO3- a base)

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12
Q

Function of bicarbonate

A
  • Neutralize acidic chyme entering duodenum from stomach
  • optimize pH for pancreatic enzyme activity
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13
Q

Name the 3 Pancreatic digestive enzymes in zymogen granules of acinar cells

A

Proteases
Lipase
Amylase

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14
Q

2 important proteases

A

Trypsinogen
Chymotrypsinogen

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15
Q

Pancreatic exocrine secretion is under _____ control by….

A

Hormonal control by hormones secreted by Enteroendocrine cells of SI

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16
Q

Hormones secreted by Enteroendocrine cells of SI

A

Secretin
Cholecystokinin (CCK)

17
Q

Function of secretin

A

Promotes water & HCO3- secretion by pancreatic duct epithelial cells

18
Q

Function of cholecystokinin (CCK)

A

Stimulate enzyme secretion by pancreatic acinar cells

19
Q

a cells secrete ____

A

glucagon

20
Q

function of glucagon

A

stimulates release of glucose into blood

21
Q

B cells secrete ____

A

insulin

22
Q

function of insulin

A

stimulates uptake of glucose from blood

23
Q

D cells secrete ____

A

somatostatin

24
Q

function of somatostatin

A

inhibits insulin & glucagon secretion

25
Q

PP cells secrete ____

A

pancreatic polypeptide

26
Q

function of pancreatic polypeptide

A

stimulate gastric chief cells, inhibits bile & exocrine pancreatic secretion

NYCC Histology (21 decks)

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