Integument System Flashcards
2 layers of the skin
epidermis & dermis
functions of integumentary system
- sensory
- thermoregulation
- metabolism
- sexual signaling
cells of the epidermis
keratinocytes
malanocytes
langerhans cells
merkel cells
karatinocytes
- most abundant cell of epidermis
- produce keratin
- form epidermal water barrier
- produce vitamin D
skin is categorized as ____ or ____
thick or thin
thick skin
- found on palms of hands and soles of feet
- 5 layers to epidermis
- subject to most abrasion, hairless
thin skin
- found everywhere except palms of hands & soles of feet
- 4 layers to epidermis
- most areas contain hair follicles
layers of epidermis
- stratum basale (stratum germinativum
- stratum spinosum
- stratum granulosum
- stratum lucidum
- stratum corneum
stratum basale (germinativum)
- single layer of mitotically active cells, rests on basement membrane, allows epidermal renewal of keratinocytes
- keratinocytes undergo keratinization, then apoptosis
stratum spinosum
thickest layer, synthesize keratin
stratum granulosum
- most superficial layer of still intact nucleated cells
- keratinocytes contain keratohyalin granules (contain keratin)
stratum lucidum
- found only in thick skin
- layer of flattened keratinocytes
- cytoplasm contains packed keratin filaments
stratum corneum
- anucleate squamous cells (keratinocytes) filled with keratin filament
- extra lipid cell layer as water barrier
- continuously shed and replenished
melanocytes produce and secrete ____
melanin
melanin
protects against mutagenic affects of UV radiation
melanin accumulates in vessels called ____
melanosomes
langerhans cells
- dendritic APCs, derived from monocytes
- present antigens to T lymphocytes in nearby lymph nodes
- mostly in stratum spinosum
merkel cells
- associated with nerve ending & function as receptors for light touch and texture (tactile sensation)
- abundant in highly sensitive skin (finger tips, bases of hair follicles)
surface of dermis has many projections called ____
dermal papillae
dermal papillae
fingerlike projections of loose CT into undersurface of epidermis
sublayers of dermis
- papillary layer
- reticular layer
sensory receptors of the skin
- meissner’s corpuscles
- pacinian corpuscles
function of meissner’s corpuscles
fine, light touch receptors
structure of meissner’s corpuscles
- encapsulated nerve ending
- unmyelinated sensory nerve fibers follow a spiral path
- Schwann cells surrounding in helical matter, forming several lamellae