Integument System Flashcards

1
Q

2 layers of the skin

A

epidermis & dermis

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2
Q

functions of integumentary system

A
  • sensory
  • thermoregulation
  • metabolism
  • sexual signaling
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3
Q

cells of the epidermis

A

keratinocytes
malanocytes
langerhans cells
merkel cells

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4
Q

karatinocytes

A
  • most abundant cell of epidermis
  • produce keratin
  • form epidermal water barrier
  • produce vitamin D
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5
Q

skin is categorized as ____ or ____

A

thick or thin

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6
Q

thick skin

A
  • found on palms of hands and soles of feet
  • 5 layers to epidermis
  • subject to most abrasion, hairless
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7
Q

thin skin

A
  • found everywhere except palms of hands & soles of feet
  • 4 layers to epidermis
  • most areas contain hair follicles
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8
Q

layers of epidermis

A
  1. stratum basale (stratum germinativum
  2. stratum spinosum
  3. stratum granulosum
  4. stratum lucidum
  5. stratum corneum
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9
Q

stratum basale (germinativum)

A
  • single layer of mitotically active cells, rests on basement membrane, allows epidermal renewal of keratinocytes
  • keratinocytes undergo keratinization, then apoptosis
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10
Q

stratum spinosum

A

thickest layer, synthesize keratin

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11
Q

stratum granulosum

A
  • most superficial layer of still intact nucleated cells
  • keratinocytes contain keratohyalin granules (contain keratin)
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12
Q

stratum lucidum

A
  • found only in thick skin
  • layer of flattened keratinocytes
  • cytoplasm contains packed keratin filaments
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13
Q

stratum corneum

A
  • anucleate squamous cells (keratinocytes) filled with keratin filament
  • extra lipid cell layer as water barrier
  • continuously shed and replenished
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14
Q

melanocytes produce and secrete ____

A

melanin

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15
Q

melanin

A

protects against mutagenic affects of UV radiation

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16
Q

melanin accumulates in vessels called ____

A

melanosomes

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17
Q

langerhans cells

A
  • dendritic APCs, derived from monocytes
  • present antigens to T lymphocytes in nearby lymph nodes
  • mostly in stratum spinosum
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18
Q

merkel cells

A
  • associated with nerve ending & function as receptors for light touch and texture (tactile sensation)
  • abundant in highly sensitive skin (finger tips, bases of hair follicles)
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19
Q

surface of dermis has many projections called ____

A

dermal papillae

20
Q

dermal papillae

A

fingerlike projections of loose CT into undersurface of epidermis

21
Q

sublayers of dermis

A
  1. papillary layer
  2. reticular layer
22
Q

sensory receptors of the skin

A
  1. meissner’s corpuscles
  2. pacinian corpuscles
23
Q

function of meissner’s corpuscles

A

fine, light touch receptors

24
Q

structure of meissner’s corpuscles

A
  • encapsulated nerve ending
  • unmyelinated sensory nerve fibers follow a spiral path
  • Schwann cells surrounding in helical matter, forming several lamellae
25
location of meissner's corpuscles
- dermal papillae - most numerous in fingertips, palms, soles
26
function of pacinian corpuscles
receptors for course touch, pressure, vibration
27
location of pacinian corpuscles
deeper dermis and hypodermis, especially in fingertips
28
structure of pacinian corpuscles
concentric lamellae of schwann cells surround unmyelinated afferent nerve fiber
29
what are hairs?
elongated keratinized structures that form within hair follicles
30
hair bulb
terminal dilation of hair follicle
31
base of hair bulb is invaginated by a well vascularized tuft of loose CT ____
dermal papillae (sustain the hair follicle)
32
hair root
portion of hair within skin
33
structure of hair root
- inner medulla (less keratinized) - cortex (heavily keratinized) - thin outer cuticle (v heavily keratinized)
34
hair follicle has an outer ____ and an inner ____
CT root sheath epithelial root sheath
35
hair shaft
external portion of hair that extends above epidermis
36
sebaceous glands secrete ____ via ____ secretion
sebum holocrine
37
sebum
- oily lipid substance that coats the hair and skin surface - cells fill with small fat droplets filled with sebum
38
holocrine secretion
cells accumulate product as they mature and enlarge, ending in rupture of cells and release of product
39
arrector pili muscle
- small bundle of smooth muscle attaches to hair follicle - contraction twists hair follicle and elevates hair, forming goosebumps - helps deliver sebum from sebaceous gland into hair follicle
40
pilosebaceous unit
1. hair follicle + hair 2. arrector pili muscle 3. sebaceous gland
41
2 types of sweat glands
eccrine and apocrine
42
function of eccrine sweat glands
produce sweat that is mostly water onto skin surface where evaporation cools the body
43
#eccrine sweat glands _____ cells surround basal aspect of secretory segment
myoepithelial cells
44
function of contraction of myoepithelial cells of eccrine sweat glands
helps release sweat from gland into ducts
45
eccrine sweat glands function via ____ secretion
merocrine
46
apocrine sweat glands contain...
slightly viscous, protein rich products (may develop odor due to bacterial activity)