Pain Flashcards
What is the function of the descending pathway that acts at the dorsal horn?
Modulates pain
- can increase or decrease its sensation
Which type of nociception fibres are myelinated?
A-delta
What is fibromyalgia?
Pain state that can’t be linked to any pathology
What is the difference between dysfunctional pain and neuropathic pain?
In neuropathic pain there is some damage to part of the NS involved in nociception while in the dysfunctional pain there is no obvious pathology
What is the nocebo effect?
A inoculous stimuli that causes pain because the subject is expecting it to be painful
Where are the cell bodies for the sensory nerves?
Dorsal root ganglia
Are all nociceptors the same?
No, different nociceptors are determined by their range of different TRPV1 receptors
What is secondary hyperalgesia?
Where increased pain sensation occurs around an area of original pain/wound
Which type of nociception fibres are unmyelinated?
C-fibres
What temperature will elicit the pain response?
>52C
<15C
Inflammation pain can lead to what changes to pain sensation?
Sensitisation to pain
Spontaneous pain
What is allodynia?
Painful response to non-noxious stimuli
Which laminae in the dorsal horn do C-fibres synapse with?
i and ii
Which type of pain fibres do glabrous skin lack? What are the implications?
Type II A fibres
They don’t have the fast response
What type of pain does stimulation of C-fibres cause?
Slow, throbbing pain
