Pagets, myositis ossificans , reactive arthritis Flashcards

1
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2
Q

pagets disease

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abnormal osteoclastic activity followed by increased osteoblastic activity resulting in abnormal bone structure and reduced strength and increased fractures

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3
Q

Risk factors for pagets

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Age >50
English, Scottish and central European
Male predominance in age group 45–74
Family history of Paget’s disease
Certain viral infections e.g. respiratory syncitial virus

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4
Q

complications of pagets

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Deafness
Osteoarthritis
Nerve compression
Fractures
Limb length discrepancy
Osteosarcoma

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5
Q

management of pagets

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Observation and prevention of complications
Bisphosphonate therapy (IV or oral)
Physiotherapy
Surgery if indicated

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6
Q

what is raised in pagets

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ALP

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7
Q

Common sites for pagets

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long bones, pelvis, lumbar spine and skull

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8
Q

xray of pagets

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  • Initial lytic phase results in well defined lucency
    • Later sclerotic phase with enlarged bone, increased density and coarse trabecular pattern
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9
Q

myositis ossificans

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abnormal formation of bone or bone-like tissue (heterotopic ossification) within large muscle groups

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10
Q

when does myositis ossificans present

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2-4 weeks ppost trauma

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11
Q

key signs and symptoms of myositis ossificans

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may mimic osteal malignancy, including pain, stiffness, and a palpable mass

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12
Q

management of myositis ossificans

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Conservative management is the primary approach, although surgical excision may be considered in severe cases.

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13
Q

common places for myositis ossificans to occur

A

elbow
thigh

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14
Q

who does myositis ossificans commonly present in

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young adults who are active in sports, particularly those involving heavy contact, which predisposes them to trauma

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15
Q

reactive arthritis

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inflammatory response to infection

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16
Q

reiters syndrome

A

conjunctibvits, urethritis, arthritis

17
Q

when does reactive arthrisi commonly presetn

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1-4 weeks post infection

18
Q

common infections invoolved in reactive arthritis

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GI/ sexually
chlamydia, neisseria
campylobacter, salmonella

19
Q

symptoms in reactive arthritis

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fever
fatigue
malaise

20
Q

what is raised in reactive arthritis

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inflammatory markers

21
Q

culture in reactive arthritis

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none
sterile
no viable organisms or its septic

22
Q

signs in reactive arthritis

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  • Mucocutaneous lesions
    • Keratodema blenorrhagica
    • Circinate balanitis
    • Painless oral ulcers
    • Hyperkeratotic nails
  • Ocular lesions (uni or bilateral) - conjuntivitis, iritis
  • Vissceral manifestations - mild renal disease, carditis
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