avascular necrosis Flashcards
what is avascular necrosis
failure of blood supply to the femoral head
results of avascular necrosis
ischameic necrosis of bone and marrow
causes for idiopathic AVN
- Coagulation of the intraosseous microcirculation
- Venous thrombosis causes retrograde arterial occlusion
- Intraosseous hypertension
- Decreased blood flow results in necrosis of a segment of bone
- There will be patchy sclerosis before subchondral collapse and irregularity of the articular surface occurs
- Resultant bone and joint damage can lead to significant structural collapse of the bone → secondary OA
- Can also secondarily affect osteoarthritic joints causing collapse of the articular surface and rapid deterioration
risk factors for AVN
irradiation
hematologic diseases (leukemia, lymphoma), sickle cell or hypercoagulable staes
dysbaric disorders (decompression sickness, “the bends”) - Caisson disease
alcoholism
steroid use
trauma
patient presentation
Insidious onset of groin pain
Exacerbated by stairs or impact
Examination is usually normal unless disease has advanced to collapse/OA
how to diagose AVN
radiographs
MRI
AVN associated with trauma
fracture disrupts the blood supply to an entire portion of bone
reversible AVN management
- If the articular surface has not collapsed in an amenable site, AVN can be reversed
- Bisphosphates
- Core decompression - drilling performed under fluoroscopy to ‘decompress’ the bone to prevent further necrosis and help healing
- Curettage and bone grafting
- Vascularised fibular bone graft
irreversible AVN management
- If the articular surface has collapsed, generally joint replacement is usually required in the hip, knee or shoulder to control symptoms
- Rotational osteotomy can be considered if less than 15% of femoral head damaged (rare)
- Fusion can be considered in the wrist or foot/ankle