MSK pathology Flashcards
what are osteophytes
bony outgrowths that develop along the edges of bones often where bones meet at joints
what do osteophytes form in response to
damaage such as when cartilage wears down causing bones to rub against another
what is eburnation
when cartilage covering the ends of bones wears away causing the exposed bone surfaces to rub directly against each other
friction smooths and polishes the bone giving it a dense ivory like appearance
radiological joint change features
Loss of joint space = cartilage loss
Subchondral sclerosis = eburnation etc
Subchondral cysts =. Synovial fluid accumulation
Osteophytes = disorganised bone remodelling
what is subchondral scleoris s
when the bone just beneath the cartilage surface known as the subchondral bone becomes hard and dense
examples of early joint changes
cracks in cartilage
later joint changes
eventually cartilage is worn away - bone on bone
eburnation occurs
cortical bone thickens to cope with load
leakage of synovial fluid through bone forming cysts
rapid remodelling of bone to cope with stress which is disorganised and produces osteophytes
what is osteomalacia
the softening of bones due to inadequate bone mineralization due to VIt D deficiency
clinical signs of osteomalacia
bowed legs, square heads, pigeon chest and rickety rosary
metabolic diseases
pagets
abnormality of bone turnover
osteomalacia
crystal arthropathies
pagets disease overvieq
Abnormal breakdown and formation of bone tissue
increased osteoclastic activity
leads to structurally abnormal enlarged and weak bones
3 stages of pagets
osteolytic; osteoclasts
mixed ; osteoclasts and osteoblasts
burnt out; chronic
role of osteoclasts
absorb bone
role of osteoblasts
form bone
