Dermatomyositis and polymyositis Flashcards
dermatomyositis
rare autoimmune rheumatic disease, characterised by distinct cutaneous manifestations and proximal muscle weakness due to myositis
clinical manifestations of dermatomyositis
gottrons papules - puprle nodules on knuckles
heliotope rash on eyelids
dry eyes, scleritis
shawl rash/ shawl sign- rash on back
common symptoms of patients with dermatomyositis
diffiuclt rising from chair
difficulty climbing stairs
difficulty raising arms
antibodies present in dermatomyositis
anti- mi1 and anti-jo1
management of dermatomyositis
corticosteroids
definitive diagnostic investigation in dermatomyositis
muscle biopsy
difference in polymyosits and dermatomyositis
dermato may have cutaneous features whereas poly is more proximal and doesnt have skin involvement
polymyositis
An inflammatory myopathy characterized by symmetrical proximal muscle weakness due to immune-mediated muscle inflammation. It primarily affects skeletal muscle
important complication to screen for
malignancy