Bone structure and MSK histology Flashcards

1
Q

variation of muscle cells

A

striated
unbranched
multinucleate

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2
Q

what are muscle fibres grouped into

A

bundles called fasicles
a muscle typically contains several fascicles

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3
Q

what is the connective tissue that surrounds the muscle as a whole

A

epimysium

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4
Q

what is the connective tissue arund a single fasicle

A

perimysium

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5
Q

what is the connective tissue around a single muscle fibre

A

endomysium

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6
Q

unit of contractio. of muscle cells

A

sarcomeres

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7
Q

type 1 muscle fibre overview

A
  • relatively slow contracting fibres
  • depend on oxidative metabolism
  • have abundant mitochondria and myoglobin
  • resistant to fatigue - produce relatively less force
  • often called ‘red’ fibres
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8
Q

type 2a muscle fibre overview

A

intermediate between the other two
- relatively fast
- reasonably resistant to fatigue
- relatively uncommon

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9
Q

type 2b muscle fibre overview

A
  • fast contracting
  • depend on anaerobic metabolism
  • few mitochondria and less myoglobin than type 1
  • fatigue relatively easy and produce greater force
  • often called white fibres
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10
Q

cartilagr v bone comparison

A

cartilage is semi rigid and deformable, permeable, avascular, cells nourished by diffusion through the extracellular matrix

bone is rigid, unpermeable, cells within the bone must be nourished by blood vessels that pervade the tissue

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11
Q

cells in cartilage

A

chondrocytes, chondroblasts when immature

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12
Q

where do chondorcytes live

A

within a space in extracellular matrix termed lacuna

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13
Q

what is the ECM compsoed of

A

type 2 collagen and proteoglycans predominantly

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14
Q

types of cartilage

A

hyaline
fibrocartilage
elastic

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15
Q

what is fibrocartilage rich in

A

collagen type 1

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16
Q

what makes up of diaphysis

A

dense cortical bone

17
Q

what makes up the epiphysis

A

cancellous or trabeccular bone
fine meshwork of bone which looks like the inside of an aero

18
Q

what type of cells do bone contain

A

osteocytes

19
Q

what is bone penetrated by

A

small canal for blood vessels and nerves

20
Q

types of bone

A

trabecular (spongy) and compact

21
Q

which cells are located on bone surfaces

A

osteoprogenitor cells

22
Q

which cellls are found on the surface of developing bone

A

osteoblasts

23
Q

which bone cell is trapped within the bone matrix

A

osteocytes

24
Q

what bone cells are responsible for bone resorption

A

osteoclasts
large multinucleated cells found on the surface of bone

25
Q

what do osteoblasts secrete

A

collagen, glycosaminoglycans, proteoglycans

26
Q

what is the collecitve term for what osteoblasts secrete

A

osteoid

27
Q

what is the mineral of bone made up of

A

calcium phosphate cyrstals

28
Q
A