P6 PATHOLOGY Flashcards
1
Q
B & T lymphocytes originates from
A
Pluripotential stem cell
2
Q
Lymphoid progenitor can develop into
A
- T cells
- B cells
Natural killer cells
3
Q
T lymphocytes leave the BM to mature in
A
thymus
4
Q
B lymphocytes mature in
A
Initially :BM
final : 2ndry lymphoid organs
5
Q
surface markers of T cells
A
CD4
CD8
6
Q
surface markers of B cells
A
MHC2
CD19
CD20
7
Q
Antigen receptor of T cells
A
TCR
8
Q
Antigen receptor of B cells
A
BCR
9
Q
CD8 meaning
A
Cytotoxic T cells
10
Q
CD4 meaning
A
helper T cells
11
Q
products secreted by T cells
A
cytokines
12
Q
products secreted by B cells
A
cytokines & antibodies
13
Q
TCR polypeptides
A
alpha & beta or
gamma & delta
14
Q
a molecule with which TCR needs to form a complex
A
CD3
15
Q
in TCR-CD3 complex , what part mediates the signal transduction
A
Cytoplasmic tail of CD3
