P3 PHYSIOLOGY

Question 1

main function of WBC

Answer 1

Resistance of the body to infections

Question 2

Mention the granulocytes

Answer 2

Neutrophils , Eosinophils & Basophils

Question 3

Mention the Agranulocytes

Answer 3

monocytes & lymphocytes

Question 4

identify this WBC

Answer 4

Lymphocyte

Question 5

identify this WBC

Answer 5

Neutrophil

Question 6

identify this WBC

Answer 6

Eosinophil

Question 7

identify this WBC

Answer 7

Monocyte

Question 8

identify this WBC

Answer 8

Basophil

Question 9

• acid hydrolases , HOCL , defensin , peroxide enzymes…etc
  all are components of

Answer 9

Non-specific granules

Question 10

Specific granules contain

Answer 10

• lysozymes , lactoferrins , bacteriostatic & bactericidal products

Question 11

Tertiary granules contain

Answer 11

• gelatinase , collagenases , hyaluronidases

Question 12

WBC that increase in bacterial infection

Answer 12

Neutrophils

Question 13

WBC that is largest in number

Answer 13

Neutrophils

Question 14

Condition in which neutrophils are increased in number

Answer 14

neutrophilia

Question 15

Condition in which neutrophils are low in number

Answer 15

neutropenia

Question 16

WBC that are increased in parasitic infection & allergies

Answer 16

Eosinophils

Question 17

color of eosinophils

Answer 17

red

Question 18

WBC that are increased in allergies

Answer 18

Basophils

Question 19

color of basophils

Answer 19

blue

Question 20

WBC that are the largest in size

Answer 20

Monocyte

Question 21

WBC that are increased in viral infections

Answer 21

Lymphocytes

Question 22

low WBC count called

Answer 22

leukopenia

Question 23

high WBC count called

Answer 23

leukocytosis

Question 24

WBC that are increased in chronic infection

Answer 24

Monocytes

Question 25

site of synthesis of lymphocytes & plasma cells

Answer 25

- thymus - lymph glands - spleen - tonsils - peyer's patches

Question 26

life span of WBC in blood

Answer 26

4-8 hrs

Question 27

life span of WBC in tissues

Answer 27

4-6 days

Question 28

monocytes in the tissues are called

Answer 28

macrophages

Question 29

life span of lymphocytes

Answer 29

weeks / months

Question 30

mention some chemical mediators of inflammation

Answer 30

Leukotrienes , interleukins , prostaglandins , histamines , TNF

Question 31

ICAM stands for

Answer 31

Intercellular adhesion molecule

Question 32

VCAM stands for

Answer 32

Vesicular adhesion molecule

Question 33

what 3 features will help in phagocytosis

Answer 33

- rough surface - dead tissue / no protection - antibody complement complex

Question 34

chemical or a protein that facilitates phagocytosis

Answer 34

Opsonin

Question 35

give 2 examples of opsonins

Answer 35

C3b , antibody IgG

Question 36

WBCs enter the tissue spaces by

Answer 36

DIAPEDESIS

Question 37

WBCs are attracted to inflamed Tissue Areas by

Answer 37

CHEMOTAXIS

Question 38

extremely bactericidal Agent

Answer 38

hypochlorite

Question 39

Enzyme that digest thick lipid membrane that is present in some bacteria

Answer 39

lipase

Question 40

Necrotic tissue , dead neutrophils & macrophages , tissue fluid all are found in

Answer 40

pus

Question 41

larvacidal polypeptide released by eosinophils are called

Answer 41

Major basic protein

Question 42

cationic proteins in eosinophils will release

Answer 42

hydrolytic enzymes

Question 43

anti-histamine enzymes released by eosinophils are called

Answer 43

Histaminases

Question 44

Substances released by basophils

Answer 44

- heparin - bradykinin - serotonin - histamine

Question 45

Antibody that causes allergic reaction

Answer 45

IgE

Question 46

Basophils will look dotted in what cases

Answer 46

- lead poisoning - anemia of chronic disease - iron def. anemia - thalassemia

Question 47

name of macrophages in kidneys

Answer 47

mesangial cells

Question 48

name of macrophages in bones

Answer 48

osteoclasts

Question 49

name of macrophages in CNS

Answer 49

microglia

Question 50

name of macrophages in lungs

Answer 50

Alveolar cells

Question 51

name of macrophages in liver

Answer 51

kupffer cells

Question 52

name of macrophages in skin

Answer 52

langerhans

Question 53

name of macrophages in spleen & lymph nodes

Answer 53

histiocytes