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UNIT 6 HEMATOLOGY > P3 PHYSIOLOGY > Flashcards

P3 PHYSIOLOGY Flashcards

1
Q

main function of WBC

A

Resistance of the body to infections

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2
Q

Mention the granulocytes

A

Neutrophils , Eosinophils & Basophils

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3
Q

Mention the Agranulocytes

A

monocytes & lymphocytes

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4
Q

identify this WBC

A

Lymphocyte

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5
Q

identify this WBC

A

Neutrophil

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6
Q

identify this WBC

A

Eosinophil

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7
Q

identify this WBC

A

Monocyte

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8
Q

identify this WBC

A

Basophil

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9
Q
  • acid hydrolases , HOCL , defensin , peroxide enzymes…etc
    all are components of
A

Non-specific granules

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10
Q

Specific granules contain

A
  • lysozymes , lactoferrins , bacteriostatic & bactericidal products
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11
Q

Tertiary granules contain

A
  • gelatinase , collagenases , hyaluronidases
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12
Q

WBC that increase in bacterial infection

A

Neutrophils

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13
Q

WBC that is largest in number

A

Neutrophils

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14
Q

Condition in which neutrophils are increased in number

A

neutrophilia

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15
Q

Condition in which neutrophils are low in number

A

neutropenia

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16
Q

WBC that are increased in parasitic infection & allergies

A

Eosinophils

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17
Q

color of eosinophils

A

red

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18
Q

WBC that are increased in allergies

A

Basophils

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19
Q

color of basophils

A

blue

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20
Q

WBC that are the largest in size

A

Monocyte

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21
Q

WBC that are increased in viral infections

A

Lymphocytes

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22
Q

low WBC count called

A

leukopenia

23
Q

high WBC count called

A

leukocytosis

24
Q

WBC that are increased in chronic infection

A

Monocytes

25
Q

site of synthesis of lymphocytes & plasma cells

A
  • thymus
  • lymph glands
  • spleen
  • tonsils
  • peyer’s patches
26
Q

life span of WBC in blood

A

4-8 hrs

27
Q

life span of WBC in tissues

A

4-6 days

28
Q

monocytes in the tissues are called

A

macrophages

29
Q

life span of lymphocytes

A

weeks / months

30
Q

mention some chemical mediators of inflammation

A

Leukotrienes , interleukins , prostaglandins , histamines , TNF

31
Q

ICAM stands for

A

Intercellular adhesion molecule

32
Q

VCAM stands for

A

Vesicular adhesion molecule

33
Q

what 3 features will help in phagocytosis

A
  • rough surface
  • dead tissue / no protection
  • antibody complement complex
34
Q

chemical or a protein that facilitates phagocytosis

A

Opsonin

35
Q

give 2 examples of opsonins

A

C3b , antibody IgG

36
Q

WBCs enter the tissue spaces by

A

DIAPEDESIS

37
Q

WBCs are attracted to inflamed Tissue Areas by

A

CHEMOTAXIS

38
Q

extremely bactericidal Agent

A

hypochlorite

39
Q

Enzyme that digest thick lipid membrane that is present in some bacteria

A

lipase

40
Q

Necrotic tissue , dead neutrophils & macrophages , tissue fluid all are found in

A

pus

41
Q

larvacidal polypeptide released by eosinophils are called

A

Major basic protein

42
Q

cationic proteins in eosinophils will release

A

hydrolytic enzymes

43
Q

anti-histamine enzymes released by eosinophils are called

A

Histaminases

44
Q

Substances released by basophils

A
  • heparin
  • bradykinin
  • serotonin
  • histamine
45
Q

Antibody that causes allergic reaction

A

IgE

46
Q

Basophils will look dotted in what cases

A
  • lead poisoning
  • anemia of chronic disease
  • iron def. anemia
  • thalassemia
47
Q

name of macrophages in kidneys

A

mesangial cells

48
Q

name of macrophages in bones

A

osteoclasts

49
Q

name of macrophages in CNS

A

microglia

50
Q

name of macrophages in lungs

A

Alveolar cells

51
Q

name of macrophages in liver

A

kupffer cells

52
Q

name of macrophages in skin

A

langerhans

53
Q

name of macrophages in spleen & lymph nodes

A

histiocytes

UNIT 6 HEMATOLOGY (33 decks)

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