P5 PHARMACOLOGY Flashcards
not the full lecture 🙏🏼
Anti-pseudomonal Penicillins route of administration
Parenterally
uses of Anti-pseudomonal Penicillins
Hospital acquired infections
Beta-lactamase inhibitors examples
Amoxicillin
clavulanate (Augmentin)
Ampicillin
sulbactam
Piperacillin
Ticarcillin
Aminoglycosides are effective against which type of bacteria
Against gram - bacteria
MOA of Aminoglycosides
*They interfere with initiation complex of peptide formation
- induce misreading of the code on the mRNA template
ADR of Aminoglycosides
-Ototoxicity
-Nephrotoxicity
-Neuromuscular blockage
-Hypersensitivity reactions
Superinfection & intestinal malabsorption
most nephrotoxic amino-glycosides
gentamicin & tobramycin
Hypersensitivity reactions can occur with which aminoglycosides
topically applied neomycin
Superinfection & intestinal malabsorption can occur following oral administration of
neomycin