P5 PHARMACOLOGY Flashcards

not the full lecture 🙏🏼

1
Q

Anti-pseudomonal Penicillins route of administration

A

Parenterally

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2
Q

uses of Anti-pseudomonal Penicillins

A

Hospital acquired infections

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3
Q

Beta-lactamase inhibitors examples

A

Amoxicillin
clavulanate (Augmentin)
Ampicillin
sulbactam
Piperacillin
Ticarcillin

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4
Q

Aminoglycosides are effective against which type of bacteria

A

Against gram - bacteria

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5
Q

MOA of Aminoglycosides

A

*They interfere with initiation complex of peptide formation
- induce misreading of the code on the mRNA template

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6
Q

ADR of Aminoglycosides

A

-Ototoxicity
-Nephrotoxicity
-Neuromuscular blockage
-Hypersensitivity reactions
Superinfection & intestinal malabsorption

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7
Q

most nephrotoxic amino-glycosides

A

gentamicin & tobramycin

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8
Q

Hypersensitivity reactions can occur with which aminoglycosides

A

topically applied neomycin

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9
Q

Superinfection & intestinal malabsorption can occur following oral administration of

A

neomycin

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