p 458 basal ganglia

Question 1

in basal gangila what are the 2 pathways that stimulate movement?

Answer 1

1. direct pathway

2. indirect pathway

Question 2

explain the role of dopamine in terms of its ability to stimulate movement

Answer 2

dopamine always make you move by inhibiting indirect pathway and stimulating direct pathway

Question 3

what dopamine receptor does direct pathway use?

Answer 3

D1

Question 4

D2 is used by what pathway?

Answer 4

indirect

Question 5

basal ganagia is important in (what particular moveiment?)

Answer 5

voluntary movements and making postural adjustment

Question 6

basal ganglia receives cortical input and provides

Answer 6

negative feedback to cortex to modulate movement

Question 7

striatum is made of what 2 components?

Answer 7

1. putamen (motor)

2. caudate (cognitive)

Question 8

lentiform is made of what 2 components?

Answer 8

1. putamen

2. globus pallidus

Question 9

explain the excitatroy pathway

Answer 9

cortical inputs stimulate the striatum –> releases GABA which blocks the thalamus via the GPi/SNr –> leads to inc motion

Question 10

explain the inhibitory pathway

Answer 10

cortical inputs stimulate the striatum –> blocks STN (subthalamic nucleus) via GPe (globus pallidus internus) and STN stimulates GPi/SNr to inhibit the thalamus –> dec motion