micro p 147-151 Flashcards
what fungus is described to have “pseudohyphae?”
Candida albicans
what fungus is described to have “narrow-base unequal budding yeast with wide capsular halo?”
Cryptococcus neoformans
what fungus is described to have “septate hyphae?”
Aspergillus fumigatus
which fungus is not dimorphic (always yeast not mold in cold)?
Cryptococcus neoformans
what agar is used to culture Cryptococcus neoformans?
Sabouraud agar
name 4 pathologic conditions associated with allergic bronchopulmonary aspergillosis?
asthma, cystic fibrosis, bronchiectasis, eosinophilia
what are red granules seen throughout RBC cytoplasm in P vivax/ovale?
Schuffner stippling
for life threatening malaria infection, what is the treatment?
IV quinidine or artesunate
what is the DOC for sensitive malaria species?
Chloroquine
what is the mech of Chloroquine?
blocks Plasmodium heme polymerase
if resistant to Chloroquine, what drug would you give?
mefloquine or atovaquone/proguanil
DOC for Babesia?
atovaquone + azithromycin
bug that causes fever, hemolytic anemia, predominantly in northeastern US
Babesiosis (Babesia)
what is the most common way to get Toxoplasma gondi?
ingesting cysts in meat
DOC for toxo?
sulfadiazine + pyrimethamine
DOC for Trypanosoma brucei?
suramin for blood borne dz or melarsoprol for CNS penetration
what is the vector for Trypanosoma brucei?
Tsetse fly (painful bite)
what is the path associated with somnolence, coma, enlarged lymph nodes, recurring fever due to antigenic variation?
African sleeping sickness by Trypanosoma brucei
which malaria species has the dormant form in liver and what is the dormant form called?
P. vivax/ovale, called hypnozoite
to kill hypnozoite what drug should be used? also before using the drug, what path must be tested?
primaquine (test for G6PD def)
what organs are affected by severe P. falciparum infection?
- Cerebral (parasitized RBCs occlude capillaries in brain)
- Kidneys
- Lungs
which malaria species has 72 hr cycle?
P. malariae
which malaria is responsible for causing fever on first day and third day?
P. vivax/ovale
name of the mosquito that spreads Malaria?
Anopheles
name the bug associated with “flask-shaped” ulcer?
Entamoeba histolytica
what is the diagnosis for Giardia lamblia?
Trophozoites or cysts in stool
what bug is associated with “cart wheel distribution of chromatin in the nucleus?
Entamoeba histolytica
what bug is associated with oocyts on acid-fast stain?
Cryptosporidium
Prevention and DOC for cryptosporidium?
prevention by filtering city water supplies and give nitazoxanide in immunocompetent host
what bug causes “ascending lymphangitis (local pustule/ulcer with nodules along draining lymphatics)?”
Sporothrix schenckii
what bug is associated with “cigar shaped budding yeast?”
Sporothrix schenckii
what are the 2 DOC for Pneumocystis jirovecii prophylaxis?
dapson, atovaquone
what stain would you use for Pneumocystis jirovecii?
methenamine silver stain
bug that looks like “disc shaped yest?”
Pneumocystis jirovecii
