micro p132-141 Flashcards
anthrax capsule is made of
polypeptide capsule (D-glutamate)
what is the preformed toxin produced by Baciluus cereus?
cereulide
bug associated with granulomatosis infantiseptica and neonatal meningitis?
Listeria monocytogenes
what is unique about Listeria as a gram positive organ?
only gram positive organism to produce endotoxin
what organism give you TB like symptoms and get stained similar to TB?
Nocardia
what is the treatment for Nocardia?
sulfonamide
which TB test has fewer false positives from BCG vaccination?
Interferon gamma release assay
what are the 2 roles of cord factor from TB?
- inhibits macrophage maturation
2. induces release of TNF-alpha
In TB, what inhibit phagolysosomal fusion?
sulfatides (surface glycolipids)
what path is associated with infection of skin and superficial nerves that lead to “glove and stocking” loss of sensation?
Leprosy (Hansen dz)
which type of leprosy is associated with low cell mediated immunity?
Lepromatous
which type of leprosy is associated with cell mediated immunity?
Tuberculoid
what type of immune response is upregulated in Lepromatous leprosy?
humoral Th2 response
what type of immune response is upregulated in Tuberculoid leprosy?
cell mediated immunity with Th1 type immune response
treatments for leprosy?
- dapson, rifampin for Tuberculoid form
2. clofazimine is added for Lepromatous form