Orthomyxoviruses - Influenza

Question 1

1) Influenzaviruses have segmented genome

Answer 1

true

Question 2

2) HPAI and LPAI strains differ in the number of basal amino acids in the HA protein

Answer 2

true

Question 3

3) HA protein of influenza viruses is responsible for the attachment to the cell

Answer 3

true

Question 4

4) The M2 protein of influenza viruses serves as an ion channel important in the decapsidation

Answer 4

true

Question 5

5) Antigenic drift means serials of point mutations in the HA and NA genes

Answer 5

true

Question 6

6) The NA protein in the influenza virus is responsible for the release from the infected cells

Answer 6

true

Question 7

7) Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the cell

Answer 7

true

Question 8

8) Genetic reassortment of human and animal influenza viruses result in the occurrence of new human influenza strains

Answer 8

true

Question 9

bats have an important role in the epidemiology of influenza

Answer 9

false

Question 10

10) Antigenic shift is behind the influenza pandemics

Answer 10

true

Question 11

11) Influenza viruses are classified into genera by their HA and NA proteins

Answer 11

false

Question 12

12) Influenza causes persistent infection in donkey

Answer 12

false

Question 13

13) The serotype of influenza viruses is determined by their HA and NA proteins

Answer 13

true

Question 14

14) The influenza viruses cause respiratory signs in sea mammals

Answer 14

true

Question 15

15) The host range of influenza virus is determined by the NA protein

Answer 15

false, determined by HA

Question 16

16) The bird to human host switch of influenza virus is mediated by swine

Answer 16

true

Question 17

17) The main host of influenza is the swine

Answer 17

false

Question 18

18) In humans inactivated vaccines are used for the immunisation against influenza

Answer 18

true

Question 19

19) Antigenic drift is behind the seasonal influenza epidemics

Answer 19

true

Question 20

20) Antigenic shift means the reassortment of the influenzavirus genome segments

Answer 20

true

Question 21

21) Influenzaviruses are sensitive to drying out

Answer 21

true

Question 22

22) For the in vitro propagation of influenza viruses embryonated eggs is used

Answer 22

true

Question 23

23) The high virulence of some influenza A viruses is the result of mutations in the HA gene

Answer 23

true

Question 24

24) Dogs are susceptible to horse origin influenza strains

Answer 24

true

Question 25

25) The HPAI strains can cause CNS Signs

Answer 25

true

Question 26

26) HPAI causes blood vessel damages and generalised infections

Answer 26

true

Question 27

27) The HPAI strains are usually developed from the H5 and H7 influenza viruses

Answer 27

true

Question 28

28) The LPAI causes immunosuppression

Answer 28

true

Question 29

29) Cat is susceptible to human seasonal influenza

Answer 29

false

Question 30

30) HPAI strains are mutations of LPAI strains

Answer 30

true

Question 31

31) HPAI strains belong into a certain haemagglutinin types

Answer 31

false

Question 32

32) Influenzas Causes enteric symptoms in human

Answer 32

false

Question 33

33) Anti-neuraminidase drugs inhibit the decapsidation of influenza viruses

Answer 33

false

Question 34

1) Swine recovered from influenza should not be kept for breeding

Answer 34

true

Question 35

2) Influenza causes high morbidity but low mortality in swine

Answer 35

true

Question 36

3) The HPAI causes skin haemorrhages in swine

Answer 36

false

Question 37

4) Swine influenza outbreaks occur usually during summer

Answer 37

false

Question 38

5) The mortality of swine influenza is high

Answer 38

false

Question 39

6) Swine influenza causes high morbidity rate

Answer 39

true

Question 40

7) To prevent complications of swine influenza penicillin injections are given to sick pigs

Answer 40

true

Question 41

8) Swine influenza is easily transmitted to people

Answer 41

false

Question 42

9) To prevent complications of swine influenza, antibiotics used

Answer 42

true

Question 43

10) In swine all influenza variants can be detected

Answer 43

false

Question 44

1) In a horse influenza outbreak all infected horses must be killed

Answer 44

false

Question 45

2) The generalized symptoms of horse influenza are result of the interferon response

Answer 45

true

Question 46

3) Racehorses should be vaccinated before the influenza season

Answer 46

false

Question 47

4) Breeding mares should be vaccinated before the influenza season

Answer 47

false

Question 48

5) Influenza causes persistent infection in horses

Answer 48

false

Question 49

1) The eggs produced in LPAI infected flock can be hatched

Answer 49

true

Question 50

2) The HPAI infection can be unambiguously differentiated from Newcastle disease by the clinical signs

Answer 50

false

Question 51

3) The HPAI strains can cause clinical signs in waterfowl

Answer 51

true

Question 52

4) In poultry farms LPAI may be endemic without clinical signs

Answer 52

true

Question 53

5) Waterfowl can carry the influenza viruses for long time

Answer 53

true

Question 54

6) Influenza viruses are shed by birds exclusively in the nasal discharge

Answer 54

false

Question 55

7) Avian influenza is zoonotic

Answer 55

true

Question 56

8) The virulence of avian influenza is determined by the i.v. pathogeny index and mortality

Answer 56

true

Question 57

9) Avian influenza can switch directly to human and cause epidemics with high case numbers as result of human to human transmission

Answer 57

false

Question 58

10) In birds all influenza variants can be detected

Answer 58

true

Question 59

11) Avian influenza of high economic impact is caused by HPAI strains

Answer 59

true

Question 60

12) Avian influenza virus is primarily spread through bronchial discharge and aerogenic route

Answer 60

false

Question 61

13) Avian influenza spread by bronchial discharge

Answer 61

true