Herpesviruses Flashcards
1) Herpesviruses are good antigens
false
2) Alphaherpesviruses are host specific slowly multiplying (>24hrs) viruses
false
3) Alphaherpesviruses may cause latent infection in neurons or ganglia
true
4) Some herpesviruses have a broad host spectrum (euryxen)
true
5) Gammaherpesviruses may cause latent infection in neurons of ganglia
true, should be false, only in lymphoid cells - alpha is in neurons
6) Herpes viruses are resistant to detergents
false
7) Herpesviruses are sensitive to detergents
true
8) Herpesviruses are generally weak antigens
true
9) Herpesviruses can cause latent persistent infections
true
10) Herpesviruses are typically stenoxen viruses, but there are significant exceptions
true
11) Herpesviruses are strong antigens, therefore single vaccinations provide lifelong protection
false
12) Herpesviruses are enveloped viruses, therefore they are sensitive to detergents
true
13) There are no serological cross-reactions between different herpesvirus species
false
14) Because the genome of herpesviruses is very stable, no attenuated mutant vaccine strains are available
false
15) Infectious bovine vulvovaginitis virus strains cause abortions and foetal deformities
false
16) Herpesvirus infections frequently result in latent virus carry
true
17) Herpesviruses usually cause latent infections and life-long virus carries
true
1) Infectious bovine rhinotracheitis virus can cause abortion.
true
2) The use of marker vaccines can help the eradication of infectious bovine rhinotracheitis virus
true
3) The most frequently used eradication strategy for IBRV is selection with the help of marker vaccines
true
4) Marker vaccines can be used in IBRV eradication programs in cattle farms
true
5) Antibodies against infectious bovine rhinotracheitis virus (IBRV) might be detected in the milk
true
6) Conjunctivitis and blepharitis are signs of infectious bovine rhinotracheitis
true
7) The infectious bovine rhinotracheitis virus (IBRV) causes haemorrhagic gastroenteritis
false
8) Infectious bovine rhinotracheitis virus also causes mastitis in cows
false
9) Infectious bovine rhinotracheitis virus is transmitted by arthropods
false
10) Infectious bovine rhinotracheitis virus can cause fatal encephalitis in calves
true
11) Infectious Bovine Rhinotracheitis virus frequently causes encephalitis in old cow and bulls
false
12) Infectious Bovine Rhinotracheitis virus frequently causes encephalitis in old sow and bulls
false
13) Infectious Bovine Rhinotracheitis can be endemic on cattle farms
true
14) Infectious bovine rhinotracheitis virus can cause skin lesions on the genitals
true
15) Bulls can shed the infectious bovine rhinotracheitis with semen
true
16) The infectious bovine rhinotracheitis virus (IBRV) may spread via semen
true
17) Pregnant cows should be immunized with inactivated vaccines against IBRV
true
18) Pregnant cows should be immunized against IBRV only with inactivated vaccine
true
19) Attenuated vaccines are used in pregnant cows against Infectious Bovine Rhinotracheitis virus
false
20) Pregnant cows can be immunized against IBRV only with attenuated vaccines
false
21) Because Bovine herpesvirus l causes latent infections; it is not possible to eradicate it from a cattle population
false
22) Bovine herpesvirus l may cause encephalitis in calves
true
23) IBRV may cause encephalitis in calves
true
24) Only inactivated vaccines are available against Bovine herpesvirus l.
false
25) Bovine herpesvirus 1 may be transmitted through semen
true
26) Seropositive cattle cannot be carriers of the Infections Rhinotracheitis virus.
false
27) Infectious Bovine Rhinotracheitis virus (IBRV) can be transmitted through vectors
false
28) The IBR virus causes nephritis in calves usually in the age between one and six months
false
29) Infectious Bovine Rhinotracheitis (IBR) cause serous nasal discharge.
false, should be true, starts off as serous and becomes mucopurulent
30) Infectious Bovine Rhinotracheitis in 6-month-old calves usually causes pneumonia.
true
31) Infectious Bovine Rhinotracheitis in cattle 6 months of age can cause encephalitis
false
32) Infectious Bovine Rhinotracheitis often cause genital lesions with vesicles
true
33) Infectious Bovine Rhinotracheitis may cause inflammation of conjunctiva.
true
34) Infectious Bovine Rhinotracheitis cause purulent discharge
true
35) In Hungary the IgE-negative marker vaccine is to be used in the control of Infectious Bovine Rhinotracheitis
true
36) Infectious Bovine Rhinotracheitis is rapidly spread within the herd
false
37) Infectious Bovine Rhinotracheitis is no longer present in Hungary
false
38) The respiratory form of Infectious Bovine Rhinotracheitis is often followed by genital symptoms
false
39) Infectious Bovine Rhinotracheitis spreads slowly within a herd
true
40) We can see characteristic clinical signs of Infectious Bovine Rhinotracheitis in day-old calves
false
41) We are doing Infectious Bovine Rhinotracheitis virus eradication programs in Hungary
true
42) Infectious Bovine Rhinotracheitis virus mainly cause encephalitis in cattle older than 6 months
false
43) Infectious Bovine Rhinotracheitis mainly causes pneumonia in 1-6 months old calves
true
44) Infectious Bovine Rhinotracheitis is rare, BHV-1 only affects cattle
false
45) In the transmission IBRV, the most important route is the germinative route
false
46) Genital form of IBR is often followed by abortion
false
47) IBR can occur in several clinical forms.
true
48) IBR is a frequent infection, cattle and its closest relatives are affected
true
1) Bovine Herpes virus 2 frequently causes abortion
false
2) Bovine herpes mamillitis virus can cause mastitis in cows
false, should be true, doesnt cause it per se but does predispose as milking is painful, so they avoid it
3) Bovine herpes mamillitis virus may cause lesions on the muzzle of suckling calves
true
4) The bovine herpes mamillitis virus causes lesions on the skin of the milkers, therefore it is a zoonotic agent
false
5) Bovine herpesvirus 2 may cause generalised skin lesions
true
6) Bovine herpesvirus 2 is the most frequent primary cause of mastitis in cattle
false
7) Bovine Herpes Mammillitis virus causes milkers’ nodules in humans
false
8) Bovine Herpes Mammillitis virus may cause lesions on the lips of milking calves
true
9) Regarding Bovine Herpes Mammillitis, mainly heifers show clinical signs
true
1) Swine inclusion body rhinitis virus is causing mainly subclinical infection
true
2) Bloody nasal discharge can be a sign of swine inclusion body rhinitis
true
3) Clinical manifestation of swine inclusion body rhinitis is usually seen in piglets less than 3 weeks old
true
4) Inclusion body rhinitis is predisposing to fatal respiratory disease in pigs
false
5) Suid herpesvirus 2 may cause upper respiratory tract disease in piglets
true
6) Swine Inclusion Body Rhinitis is usually seen in piglets
true
7) The Swine Inclusion Body Rhinitis virus may cause reproductive problems in sows
true
1) Malignant catarrhal fever is mostly fatal in sheep
false
2) Malignant catarrhal fever is an alphaherpesvirus causing latent infection in ganglia
false
3) Malignant catarrhal fever develops only in suckling calves up to two weeks of age
false
4) Malignant catarrhal fever can be seen only in calves younger than one month
false
5) Malignant catarrhal fever causes only mild respiratory disease in sheep
false
6) Sheep should be immunised against malignant catarrhal fever virus
false
7) Malignant catarrhal fever may develop in swine too
true
8) Malignant catarrhal fever is frequently seen in cats
false
9) Cattle should be vaccinated against malignant catarrhal fever
false
10) Goats are the reservoir hosts of the malignant catarrhal fever virus
false
11) The incubation period of malignant catarrhal fever is less than one week
false
12) Malignant catarrhal fever is quickly spreading from cattle to cattle.
false
13) Cattle should be vaccinated against malignant catarrhal fever in every six months
false
14) The malignant catarrhal fever is caused by Bovine Herpes virus-2
false
15) Malignant Catarrhal Fever is usually lethal in cattle
true
16) Rodents are the reservoir hosts of the Malignant Catarrhal Fever virus
false
17) Swine are the reservoir host of the Malignant Catarrhal Fever virus
false
18) The Malignant Catarrhal Fever is caused by Bovine herpesvirus-2
false
19) We vaccinate calves 2 times against Malignant Catarrhal Fever
false
20) Swine are affected by Malignant Catarrhal Fever
true
21) Malignant Catarrhal Fever does not occur in Europe
false
22) Malignant Catarrhal Fever can cause diarrhoea
true
23) Malignant Catarrhal Fever spreads slowly within a cattle herd
false
24) Malignant Catarrhal Fever occurs if we keep cattle and sheep together
true
25) Malignant Catarrhal Fever does not occur in Hungary
false
1) The Aujeszy’s disease virus is stenoxen
false
2) Wild boars are not susceptible to Aujeszy’s disease virus.
false
3) Abortion of sows can be a sign of Aujeszys disease
true
4) Pregnant sows may abort in Aujeszky’s disease
true
5) In swine the most serious CS of Aujeszys disease are usually seen in piglets
true
6) Dogs should be vaccinated against Aujeszys disease
false
7) Carnivores are the reservoir hosts of the Aujeszky’s disease virus
false
8) The Aujeszys disease in cats is usually a mild respiratory disease with quick recovery
false
9) The signs of Aujeszys disease in dogs are similar to rabies
true
10) The natural reservoir hosts of the Aujeszys disease virus are rodents
false
11) The Aujeszy disease causes fatal pneumonia in Ruminants and Carnivores
false
12) The Aujeszy disease is zoonosis
false
13) The symptoms of Aujeszys disease in ruminants is similar to rabies
true
14) The Aujeszy disease virus may infect several mammalian hosts
true
15) Aujeszys diseases can be latently carried by pigs in the nervous system
true
16) Central nervous signs of the Aujeszky’s disease are rarely seen in adult swine
true
17) Convalescent swine are life-long carriers and potential shedders of Aujeszky’s disease virus
true
18) Swine are immunized against the Aujeszky’s disease virus usually with gE negative marker vaccines
true
19) Rats are the reservoir hosts of the Aujeszky’s disease
false
20) The Suid herpesvirus 1 frequently causes encephalitis in humans
false
21) Liquid manure may play a role in the transmission of Suid herpesvirus 1 from swine to cattle
true
22) Discriminative ELISA tests may differentiate between vaccinated swine wild type Suid- herpesvirus infected ones
true
23) In adult swine the most frequent manifestation of Aujeszky’s disease is encephalitis
false
24) Aujeszky’s disease virus infection in adult pigs is frequently subclinical
true
25) Pigs infected with wild type Aujeszky’s disease virus can be differentiated from vaccinated ones by serological tests (i.e ELISA).
true
26) Cattle should be vaccinated against Malignant Catarrhal Fever
false
27) Aujeszky ́s disease can occur in pigs and cats
true
28) Aujeszky ́s disease in pigs causes viraemia
true
29) Aujeszky ́s disease in cats spreads along the nerves
true
30) Aujeszky ́s disease can cause respiratory signs in adult pigs
true
31) Aujeszky ́s disease causes fever in day old piglets
true
32) Aujeszky`s disease causes pneumonia in susceptible piglets
false
33) Aujeszky`s disease doesn’t cause clinical signs in susceptible piglets
false
34) Aujeszky`s disease causes pruritus in susceptible piglets.
false
35) Aujeszky`s disease causes 20-30% mortality in susceptible piglets.
false
36) Older pigs are more frequently affected by Aujeszky ́s
false
1) Equine rhinopneumonitis virus is transmitted by arthropods
false
2) For immunisation against equine rhinopneumonitis virus mostly marker vaccines are used
false
3) Equine rhinopneumonitis virus can cause abortion several weeks after acute infection.
true
4) Equine rhinopneumonitis virus causes cytoplasmic inclusion bodies in the foetal hepatocytes
false
5) Equid herpesvirus 4 more frequently causes encephalitis than Equid herpesvirus 1
false
6) Horses should be vaccinated against equine rhinopneumonitis virus at least every 6 months
true, should be false
7) Equine rhinopneumonitis virus causes necrotic foci in the liver of the foetus
true
8) Fever and serous nasal discharge are early signs of acute equine rhinopneumonitis
true
9) Equine rhinopneumonitis virus can cause purulent metritis
false
10) Only equine herpesvirus 4 can cause abortion
false
11) Pregnant mares abort usually in the acute phase of equine rhinopneumonitis
false
12) After EHV1 infection pregnant mares abort in the acute febrile stage
false