Non-Ischaemic Myocardial Disease Flashcards

1
Q

What are the clinical features of arrhythmogenic right ventricular dysplasia?

A

non-specific - difficult to diagnosis, syncope

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2
Q

What are the causes of restrictive cardiomyopathy?

A

deposition of metabolic by-products or amyloid inn myocardium, sarcoid, tumours, fibrosis

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3
Q

What are the causes of dilated cardiomyopathy?

A

genetic, alcohol, chemotherapy, infection, pregnancy

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4
Q

What are the complications of arrhythmogenic right ventricular dysplasia?

A

arrhythmias, sudden death

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5
Q

What are the complications of hypertrophic cardiomyopathy?

A

sudden death - especially in athletes

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6
Q

What happens in restrictive cardiomyopathy?

A

stiff heart - lack of compliance - diastolic dysfunction

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7
Q

What is the histology of hypertrophic cardiomyopathy?

A

disorganised myofibrils - swirls

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8
Q

What is the appearance of the heart in restrictive cardiomyopathy?

A

normal

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9
Q

What is the appearance of the heart in dilated cardiomyopathy?

A

big, flappy, floppy heart

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10
Q

What are the clinical features of dilated cardiomyopathy?

A

heart failure, dyspnoea, poor exercise tolerance, low CO

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11
Q

What happens in arrhythmogenic right ventricular dysplasia?

A

right ventricle largely replaced by fat

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12
Q

What is sarcoid?

A

multi-system granulomatous disorder

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13
Q

What is Dressler’s syndrome?

A

post MI - damaged heart muscle releases previously unencountered material - stimulates immune response

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14
Q

What is the appearance of the heart in hypertrophic cardiomyopathy?

A

big, solid heart

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15
Q

What are the causes of hypertrophic cardiomyopathy?

A

mainly genetic

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16
Q

What is the appearance of the heart in arrhythmogenic right ventricular dysplasia?

A

big and floppy

17
Q

What are the causes of arrhythmogenic right ventricular dysplasia?

A

genetic disease - autosomal dominant - low penetrance

18
Q

What happens in hypertrophic cardiomyopathy?

A

thicken wall - LV luminal reduction

19
Q

What can cause non-infectious myocarditis?

A

hypersensitivity to infection - rheumatic fever after Strep. sore throat, hypersensitivity to drugs - eosinophilic myocarditis, systemic lupus erythematosus

20
Q

What are the complications of pericarditis?

A

pericardial effusion, tamponade, cardiac failure, death

21
Q

What is amyloid?

A

abnormal protein - waxy pink

22
Q

What is the result of infectious myocarditis?

A

thickened beefy myocardium

23
Q

What causes pericarditis?

A

infection, rheumatic, uraemic (renal failure), Dressler’s syndrome, connective tissue disease

24
Q

What are the signs of hypertrophic cardiomyopathy?

A

jerky pulse, double apex beat, ejection systolic murmur

25
Q

What are the symptoms of hypertrophic cardiomyopathy?

A

dyspnoea, angina, syncope