Anti-Platelets

Question 1

What is tirofiban used for?

Answer 1

prevent MI in high risk patients with unstable angina with aspirin and heparin

Question 2

What are the adverse effects of aspirin?

Answer 2

GI bleeding and ulceration

Question 3

How is clopidogrel administered?

Answer 3

oral

Question 4

What colour is an arterial thrombosis?

Answer 4

white

Question 5

What is clopidogrel?

Answer 5

a prodrug requiring hepatic metabolism

Question 6

What forms an arterial thrombosis?

Answer 6

mainly platelets in a fibrin mesh

Question 7

When is clopidogrel used?

Answer 7

patients intolerant to aspirin (expensive)

Question 8

What is the mechanism of action of clopidogrel?

Answer 8

irreversibly inhibits P2Y12 adenosine diphosphate receptor - prevents platelet activation

Question 9

How is aspirin administered?

Answer 9

oral

Question 10

How is tirofiban administered?

Answer 10

IV short term

Question 11

What is aspirin used for?

Answer 11

prophylaxis in patients at high CVS risk

Question 12

What is the mechanism of action of aspirin?

Answer 12

irreversibly blocks cyclooxygenase (COX) in platelets - COX inhibits production of antithrombotic prostaglandin I2