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Pharma Caro > NO/cGMP-System > Flashcards

NO/cGMP-System Flashcards

1
Q

Glyzeroltrinitrat

A

NO-Donator

enzymatische Freisetzung von NO und damit sGC-Aktivierung, Relaxation glatte Muskelzellen

Angina pectoris
hypertensive Krise
Kolikschmerzen
verzögerte Giftresorption nach Schlangenbissen

Ortosthase
Flush
Tachykardie
Nitratkopfschmerz

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2
Q

Natriumnitroprussid

A

NO-Donator

Nicht-enzymatische Freisetzung von NO und sGC-Aktivierung, Relaxation glatte Muskelzellen

hypertensive Krise

Hypotonie, Zyanid-Intoxikation

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3
Q

Riociguat

A

sGC-Stimulator

NO-abhängige sGC-Stimulation (allosterische Verstärkung der Wirkung von NO an sGC), Relaxation glatter Muskelzellen

PAH

BD-Abfall

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Pharma Caro (32 decks)

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