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Pharma Caro > Antiviral > Flashcards

Antiviral Flashcards

1
Q

Aciclovir

A

DNA-Polymerase-Inhibitor

Herpes simplex (HSV), Varizella Zoster (VZV)

Nierenkollik bei zu hoher IV-Dosis
Schwindel, Kopfschmerzen, Übelkeit

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2
Q

Ganciclovir

A

HHV5, Cytomegalievirus

Nierenkolliken bei zu hoher IV-Dosis

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3
Q

Elvitegravir

A

Integrase-Inhibitor

HIV

Diarrhoe, Emesis, Nausea, Kopfschmerzen, Fieber

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4
Q

Raltegravir

A

HIV
ua Postexpressionsprophylaxe

Diarrhö, Emesis, Nausea, Fieber, Kopfschmerzen

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5
Q

Nevirapin

A

HIV

rasche Resistenzbildung

Allergie, Lebertoxizität, NICHT teratogen

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6
Q

Efavirenz

A

NNRTI

HIV

rasche Resistenzbildung

TERATOGEN
ZNS-Störungen (Schwindel, Somnolenz, Schlafstörungen, Albträume)
Hautausschläge

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7
Q

Abacavir

A

NRTI

HIV

schwere Typ-4-Allergien - Überempfindlichkeitsstörungen!!!!!!
GI, ZNS, Hepatomegalie, Hepatitis

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8
Q

Emtricitabin

A

NRTI

Präexpositionsprophylaxe HIV mit Tenofovir
Hepatitis B

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9
Q

Tenofovir

A

NRTI

Präexpositionsprophylaxe HIV mit Emtricitabin

NIERENFUNKTIONSTÖRUNGEN

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10
Q

Ledipasvir

A

NS5A-Inhibitor

HCV

gut verträglich

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11
Q

Sofosbuvir

A

NS5B-Inhibitor

Polymerasehemmer

HCV

Anämie, Nausea, Emesis, Kopfschmerzen

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12
Q

Atazanavir

A

Protease-Inhibitor

HIV

CYP3A4Inhibitor

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13
Q

Simeprevir

A

Protease-Inhibitor

HCV

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14
Q

Ribavirin

A

RNA-Polymerase-Inhibitor

HCV
Influenzaviren
Herpesviren

reversible hämolytische Anämie
Teratogen!

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Pharma Caro (32 decks)

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