Neuro psych Test 6 11 and 8 Flashcards
What evidence indicates that humans have an internal biological clock?
People who have lived in an environment with a light-dark schedule much different from 24 hours fail to follow that schedule and instead become wakeful and sleepy on about a 24-hour basis
why do people at the eastern edge of Germany awaken earlier than those at the western edge on their weekends and holidays?
The sun rises about half an hour earlier at the eastern edge than at the western edge. Evidently, the sun control waking-sleeping schedules even when people follow the same clock time for their work schedule.
What evidences strongly indicates that the SCN produces the circadian rhythm itself?
SCN cells produce a circadian rhythm of activity even if they are kept in cell culture isolated form the rest of the body. Also, when hamsters received transplanted SCN neurons, their circadian rhythm followed the pattern of the donor animals.
How does light reset the biological clock?
A branch of the optic nerve, the retinohypothalamic path, conveys information about light to the SCN. The axons comprising that path originate from special ganglion cells that respond to light by themselves, even if they do not receive input from rods or cones
Someone who is blind because of cortical damage can still synchronize his or her circadian rhythm to the local pattern of day and night. Why?
If the retina is intact, melanopsin-containing ganglion cells can still send messages to the SCN, resetting its rhythm.
How do the proteins TIM and PER relate to sleepiness in Drosophila?
The proteins TIM and PER remain low during most of the day and begin to increase toward evening. They reach high levels at night, promoting sleep. They also feed back to inhibit the genes that produce them, so that their level declines toward morning.
What conclusion do researchers draw from the observation that workers on submarines are unable to adjust to a schedule of working 12 hours and resting 6 hours
the human body generates a circadian rhythm.
Why do people in Antarctica during the winter often find it difficult to work together?
The circadian rhythms drift out of phase with one another
If workers rotate between working shifts at different times of day, what would be a good way to help them adjust to the night shift?
Use bright lighting during the night shift
What tends to be characteristic of teenagers who are extreme “evening” types
They got worse grades in school than their abilities would predict.
What evidence strongly indicates that the SCN produces the circadian rhythm itself?
SCN cells isolated from the body continue to produce a circadian rhythm.
Light resets the biological clock by a branch of the optic nerve, beginning with —– and sending the input to ——
ganglion cells that do not require input from rods or cones….. the SCN
If you want to get sleep on time, what should you avoid?
Short-wavelength light late in the evening
The proteins TIM and PER reach their highest levels—-. They —– the activity of the genes that produce them.
At night/inhibit
What do large, slow waves on an EEG indicate?
Large, slow waves indicate a low level of activity, with much synchrony of response among neurons.
How can an investigator determine whether a sleeper is in REM sleep?
Examine EEG pattern and eye movements.
During which part of a night’s sleep is REM most common?
REM becomes more common toward the end of the night’s sleep.
Why do most antihistamines make people drowsy?
Two paths from the hypothalamus - one to the basal forebrain and one to the pontomesencephalon - use histamine as their neurotransmitter to increase arousal. Antihistamines that cross the blood-brain barriers blocks those synapses.
What would happen to the sleep-wake schedule of someone who lacked orexin?
Someone without orexin would alternate between brief periods of waking and sleeping.
What would happen to the sleep wake schedule of someone who took a drug that blocked GABA?
Someone who took a drug that blocks GABA would remain awake. (Tranquilizers put people to sleep by facilitating GABA)
Someone who has just awakened sometimes speaks in a loose, unconnected, illogical way. How could you explain this finding?
People often awaken from a REM period because REM is abundant toward morning when people usually awaken. Different brain areas don’t wake up all at once. Shortly after awakening, parts of the brain may still be in a REM-like state, and thinking may have an illogical, dreamlike quality.
What kinds of people are most likely to develop sleep apnea?
Sleep apnea is most common among people with a genetic predisposition, old people, and overweight middle-aged men.
What is the relationship between orexin and narcolepsy?
Orexin is important for staying awake. Therefore, people or animals lacking either orexin or the receptors for orexin develop narcolepsy, characterized by bouts of sleepiness during the day.
Slow, large-amplitude EEG waves characterize which stage or stages of sleep?
Stage 3 and 4
Why is REM sleep also known as paradoxical sleep?
It is deep sleep in some ways and light in others.
At which time if any, is stage 4 sleep most common?
Not immediately, but during the early part of the night’s sleep.
Of the following, which two neurotransmitters increase arousal in the brain?
Acetylcholine and histamine
Norepinephrine, released by the locus coeruleus, has which effect on behavior?
It increases attention to important information.
How do dolphins handle breathing while they are asleep?
Half of the brain sleeps while the other remains awake enough to surface and breathe.
What does PGO stand for (with regards to brain function)?
Protein-Geniculate-Outcome
If you awaken but find you temporarily cannot move your arms or legs, what is happening?
Most of your brain is awake, but part of your pons and medulla remain in REM sleep.
Of the following, which one is NOT associated with an increased probability of sleep apnea?
being female
Narcolepsy is linked to a deficit of which neurotransmitter?
Orexin
When does sleepwalking usually occur?
During slow-wave sleep (stages 3 and 4)
What kind of animal tends to get more than the average amount of sleep?
Predators get much sleep, and so do species that are unlikely to be attacked during their sleep (such as armadillos)