MPQ- MIDTERM 8 Flashcards
The resting membrane potential is a value between??
-50 mV and -100mV
What is characteristic of the function of ventral posteromedial (VPM) thalamic nuclei?
A. They belong to the so-called bypass nuclei
B. The trigeminal nerve is the most important afferent of them
C. Afferent informations come from the spinothalamic tract
D. there is no somatotopic localization in them
B. The trigeminal nerve is the most important afferent of them
What is characteristic of the bypass nuclei of the thalamus?
A. afferent informations come from the spinothalamic tract
B. the trigeminal nerve is the most important afferent of them
C. none of the axons of its neurons leave the thalamus
D. their other name is “relay nuclei”
C. none of the axons of its neurons leave the thalamus
Which is true for the cortical sensory areas?
A. The secondary sensory area can be found in the postcentral gyrus
B. by removal the localization of the pain does not change
C. the main function of them is to establish the emotional aspects of pain
D. the postcentral gyrus is the main center of the tactile, mechanical and thermal sensation as the primary sensory area
D. the postcentral gyrus is the main center of the tactile, mechanical and thermal sensation as the primary sensory area
Which is true for the “columnar module” ?
A. each of them contains about 2500 cells of which 5% are pyramidal cells
B. pyramidal cells are the main afferent cells of it
C. Martinotti cells are the main efferent cells of it
D. Cajal`s cells belong to the efferent group of the column
A. each of them contains about 2500 cells of which 5% are pyramidal cells
Knowing the somatotopic localization of the cortex, which is true for the postcentral gyrus of different species?
A. in the dog 60% of the sensory area represents the lip
B. in the rabbit 60% of the sensory area represents the lip
C. in the monkey 30% of the sensory area represents the anterior limb
D. in the rabbit 90% of the sensory area represents the periocular
B. in the rabbit 60% of the sensory area represents the lip
Which area initiates the movements in the brain ?
A. the praecentral motor cortex
B. the area of the basal ganglia
C. limbic, orbitofrontal or hypothalamical area
D. association cortex
C. limbic, orbitofrontal or hypothalamical area
Which area is the main motility planning area in the brain ?
A. the praecentral motor cortex
B. the area of the basal ganglia
C. the limbic, orbitofrontal or hypothalamical area
D. the association and motor cortex
D. the association and motor cortex
Which area is responsible for the execution of movements in the brain ? A. the preacentral cortex B. the area of the basal ganglia C. the postcentral cortex D. the association and motor cortex
A. the preacentral cortex
Which of the followings belongs to the so-called Sherrington`s "final common pathway" of the motor systems? A. to the upper motor system ( UMS ) B. to the lower motor system ( LMS) C. to the motor planning system D. to the brain stem motor center
B. to the lower motor system ( LMS)
What is true for the macula of the of vestibular apparatus? A. it senses the rotational acceleration B. it records dynamical changes C. it mediates static informations D. it can be found in the ampullas
C. it mediates static informations
What happens if the sterocilia move toward the kinocilium in the vestibular apparatus?
A. the membrane of the receptors hyperpolarize
B. the mean discharge frequency does not change significantly in the vestibular nerve
C. the mean discharge frequency decreases in the vestibular nerve
D. potassium influx and consequent depolarization
D. potassium influx and consequent depolarization
What is true for the vestibular tract?
A. centripetal fibers go to the lateral (Deiters) nucleus of the vestibular ganglion from the ganglion Scarpae
B. efferent fibers go to the sacculus from the nucleus Deiters
C. fibers go to the oculomotor nuclei from the vestibular nuclei without switching over
D. no direct fibers go to the cerebellum from the nucleus Deiters
A. centripetal fibers go to the lateral (Deiters) nucleus of the vestibular ganglion from the ganglion Scarpae
Which transection leads to decebrate rigidity?
A. below vestibular ganglia
B. between nucleus ruber and nucleus Deiters
C. under the nucleus of the phrenical nerve
D. over the ruber nucleus
B. between nucleus ruber and nucleus Deiters
What is the function of the statocinetic reflexes?
A. anti gravitational support
B. connecting eye and neck muscles
C. they responsible for postural refexes evoked by kinetic stimuli
D. they responsible for the support of body mass centre in place
C. they responsible for postural refexes evoked by kinetic stimuli
Which postural reflex is initiated during dropping a cat turned upside down? A. tonic reflex B. statocinetic reflex C. stepping out reflex D. erecting reflex
D. erecting reflex
In which order are the centers of the motor cortex acivated?
A. supplementer cortex, premotor cortex, primary motor cortex
B. supplementer cortex is the last in order
C. primary motor cortex is the first in order
D. the premotor cortex is the last in order
A. supplementer cortex, premotor cortex, primary motor cortex
What is the function Brodman 8 area of the motor cortex ?
A. this is the primary motor center
B. as a “stare”-center directs the eye movements in concert with body movements
C. this is the secondary motor center
D. as a supplementer cortex initiates movements
B. as a “stare”-center directs the eye movements in concert with body movements
What happens at the unilateral transection of the pyramidal tract in primates?
A. voluntary movements are ceased
B. decebration rigidity takes place
C. flaccid paralysis of muscles on the other side
D. fine movements are undamaged
C. flaccid paralysis of muscles on the other side
What percentage of the pyramidal tract is crossed over in the pyramidum? A. about one third of it B. 100% C. about half of it D. 80%
D. 80%
Which of the following functions do not belong to the basal ganglia related to the direction of movements?
A. sends direct efferentation to the alpha-motoneurons of the spinal cord
B. movements are initiated here
C. influences the extent of thalamocortical activity
D. gives emotional afferentation for the regulation of movements
A. sends direct efferentation to the alpha-motoneurons of the spinal cord
Which symptom takes place in Parkinson disease?
A. thalamocortical activity decreases
B. dopamin production is ceased in the substantia nigra
C. pallidum activity decreases
D. the brain stem is under increased inhibition
B. dopamin production is ceased in the substantia nigra
Which of the following statements is true?
A. vestibulocerebellum is phylogenetically the newest part of the cerebellum
B. the efferent function of spinocerebellum is realized by the Fastigial nucleus
C. the efferent function of spinocerebellum is realized by the dentate nucleus
D. cerebrocerebellum gets information from the motor cortex by the thalamus
C. the efferent function of spinocerebellum is realized by the dentate nucleus
What is true for the cerebellar module ?
A. afferentation reaches the module bypassing the cerebellar nuclei
B. mossy fibers reach directly the Purkinje cells from the olive
C.climbing fibers synaptize on the granular cells
D. it has three inhibitory neuron: Pukinje cells,stellar cells and basket cells
D. it has three inhibitory neuron: Pukinje cells,stellar cells and basket cells
What is characteristic of the Purkinje cells of the cerebellum?
A. they inhibit the efferent nuclei of the cerebellum
B. they faciltate the efferent nuclei of the cerebellum
C. their activity decrease by increasing the activity of granular cells
D. their neurotransmitter is glutamate
A. they inhibit the efferent nuclei of the cerebellum
What does dys-diacho-kinesis mean?
A. flaccid, paralysed state
B. Incoordination of fast, alternating movements because of an injury of the cerebellum
C. placing reflex of the limbs is diminished
D. impaired distance estimation during movements because of removal of cerebellum
B. Incoordination of fast, alternating movements because of an injury of the cerebellum
What is the reason of after-hyperpolarization?
A. influx of sodium ions
B. calcium influx into the cell
C. slight chlorid ion outflow occurs
D. voltage-dependent potassium channels close too slowly
D. voltage-dependent potassium channels close too slowly
Which statement is true for the propagation of action potential?
A. TTX-sensitive sodium channels can only be found at the nodes of Ranvier along the myelinated fibre
B. between the nodes the resistence is low
C. between the nodes the capacity is very high
D. in the nodes of Ranvier the response propagates with a decrement
A. TTX-sensitive sodium channels can only be found at the nodes of Ranvier along the myelinated fibre
What is the internationally accepted term for unmyelinated, naked nerve fibers? A. Erlanger-Gasser type Alpha Group B. Lloyd-Hunt Type Group IV C. Erlanger-Gasser Type Agamma Group D. Lloyd-Hunt Type Group I.
B. Lloyd-Hunt Type Group IV
Which statement is characteristic of the electric synapses consisting of gap junctions?
A. they consist of three connexin peptides
B. they are characterized by slow conduction
C. they conduct in both directions, sometimes they rectify
D. they made up of six pairs of connexin peptides
C. they conduct in both directions, sometimes they rectify
Which is not true for the metabotropic mechanism?
A. it generates a slow, long lasting response
B. in most of the cases it causes a long lasting alteration of calcium conductance
C. A typical example of it is the intracelular cAMP-reducing effect of norepinephrine
D. fast response, generated by IPSP or EPSP
D. fast response, generated by IPSP or EPSP
Which is the correct classification of the receptor of hearing?
A. according to the type of its receptor cells the organ of hearing contains secondary receptors
B. the organ of hearing is a primary sensory organ
C. the organ of hearing is a tertiary sensory organ
D. according to the degree of adaptation the organ of hearing contains fast adapting receptors
A. according to the type of its receptor cells the organ of hearing contains secondary receptors
Which of the following receptors have free nerve endings?
A. the pacinian corpuscle
B. the pain- and temperature sensing exteroceptors
C. the Krause corpuscle
D. the Merkel cell ending
B. the pain- and temperature sensing exteroceptors
What happens in the receptor during “transduction”?
A. the external sitmulus opens voltage-dependent sodium channels
B. the external stimulus generates an action potential
C. the external stimulus creates a generator potential
D. a frequency coded electric signal is generated
C. the external stimulus creates a generator potential
How many major parts does the voltage-dependent sodium channel consist of? A. 7 transmembrane components B. 3 peptide chains C. 9 subunits D. 5 transmembrane components
D. 5 transmembrane components
Which statement is true for the nicotinic acetylcholine receptor?
A. the skeletal muscle type receptor consists of 2 alpha, 2 beta and 1 delta units
B. the neural type receptor is particularly sensitive to the curare
C. the neural type receptor contains three alpha subunits
D. its agonist is the isoproterenol
A. the skeletal muscle type receptor consists of 2 alpha, 2 beta and 1 delta units
Which statement is true for the glutamate receptor?
A. it is activated only by high frequency presynaptic AP
B. it has three subtypes: NMDA, AMPA and kainate
C. it primarily can be found on the postsynaptic membranes of the peripheral nervous system
D. its opening causes selective sodium influx
B. it has three subtypes: NMDA, AMPA and kainate
Which of the following receptors belongs to the group stimulating the opening of the G-protein coupled cation channel? A. adrenerg beta2 receptor B. AMPA receptor C. dopamine-D2 receptor D. nicotinic acetylcholine receptor
C. dopamine-D2 receptor
What is characteristic of the so-called energy sensor receptor?
A. when it is activated, potassium leaves the cell
B. it is opened, closed or inactivated by neurotransmitters
C. its operation is G-protein dependent
D. its specific activator is the increse of the intracellular ATP level
D. its specific activator is the increse of the intracellular ATP level
What is characteristic of the so-called ryanodine sensitive calcium channel?
A. it is located on the membrane of the sarcoplasmic reticulum
B. it acts as a voltage sensor
C. it carries calcium from the cytoplasm to the sarcoplasmic reticulum
D. it opens upon electric stimulus
A. it is located on the membrane of the sarcoplasmic reticulum
What is characteristic of the so-called DHP (dihydropyridine) sensitive calcium channel of the skeletal muscle?
A. it is located on the membrane of the sarcoplasmic reticulum
B. it activates the ryanodine sensitive calcium channel as a voltage sensor
C. it carries calcium from the cytoplasm to the sarcoplasmic reticulum
D. it opens upon chemical stimulus
B. it activates the ryanodine sensitive calcium channel as a voltage sensor
Which substance opens the ligand dependent intracellular calcium channel? A. DAG B. aldosterone C. IP3 D. thyroxines
C. IP3
What is the cause of the summation?
A. inactivation of voltage dependent cation channels
B. summation of the electric effects of the stimulus
C. outflow of anions from the cell due to repeated stimuli
D. presence of a relatively slow cation-removing system
D. presence of a relatively slow cation-removing system
Which is the proper definition for chronaxia?
A. chronaxia is the time period necessary for generating an AP in the case of stimulation with the double of the rheobasis
B. chronaxia is the extent of the stimulus twice as large as the treshold stimulus
C. chronaxia means the time period necessary for achieving the firing level in the case of maximal stimulation
D. the measure for chronaxia is mV or V
A. chronaxia is the time period necessary for generating an AP in the case of stimulation with the double of the rheobasis
How many major components compose the classical spinal cord refelex? A. afferent and efferent parts B. 5 major components C. receptor, center and effector parts D. central and peripheral pathways
B. 5 major components
What is the proper definition for the disinhibition occurring in the neural networks?
A. stimulation of the neurons generating EPSP
B. inhibition of the facilitating neurons
C. inhibition of the neurons generating IPSP
D. facilitation of the reverberation cycle
C. inhibition of the neurons generating IPSP
occurs on the postsynaptic membrane in case of monosynaptic inhibition? A. EPSP B. Increased AP discharge C. MEPP D. IPSP
D. IPSP
What is characteristic of the movement patterns of the spinal cord?
A. stereotypia
B. they cover one segment
C. they are not repetitive
D. they ceased immediately after the stimulation
A. stereotypia
Which is characteristic of the myotatic reflex?
A. it is composed of a polysynaptic reflex arc
B. it is composed of a monosynaptic reflex arc
C. the response lasts long after the stimulation
D. this reflex is “fatigable”
B. it is composed of a monosynaptic reflex arc
What is characteristic of the exteroceptive reflex?
A. monosynaptic reflex arc
B. it is not fatigable
C. it is composed of a widespread polysynaptic network
D. it does not evoke contralateral responses
C. it is composed of a widespread polysynaptic network
Which of the following reflexes - also used in the clinical practice - is proprioceptive? A. scrotum reflex B. patelar reflex C. whither reflex D. plantar reflex
D. plantar reflex
Which of the followings is an exteroceptive reflex also used in the clinical practice? A. withers reflex B. patella reflex C. frontal carpus reflex D. the dorsal reflex bellow hock
A. withers reflex
Which definition describes most appropriately the Babinski reflex?
A. this reflex is a typical proprioceptive reflex
B. dorsal flexion of the toe is characteristic of this reflex because of the deficiency of cortical control
C. the reflex is a normal flexor reflex
D. pathological response, which takes place while evoking patella reflex
B. dorsal flexion of the toe is characteristic of this reflex because of the deficiency of cortical control
Which of the following factors is the most important according to the up-to-date explanation of inverse myotatic reflex?
A. the Golgi’s tendon receptors
B. the cortical modulation
C. the deep type III receptors during active physical work of the muscle
D. the sudden passive tension of the muscle
C. the deep type III receptors during active physical work of the muscle
Which statement is true for the “extensor-thrust” phenomenon?
A. It is a typical exteroceptive reflex
B. the flexion of the interosseal muscles is characeteristic of it
C. it plays an important role in defense
D. its role is to ensure the support during executing a step
D. its role is to ensure the support during executing a step
What is the role of the Renshaw cells in the spinal chord in the course of myotatic reflex?
A. inhibitory cells blunting the strong afferent effects
B. they facilitate the function of the gamma loop
C. they inhibit the motor neurones of contralateral flexors
D. they transmit the effects of the vestibulospinal pathways
A. inhibitory cells blunting the strong afferent effects
What kind of fibers conduct the action potential from the Golgi's tendon receptors? A. type Ia B. type Ib C. type II D. type C unmyelinated fibers
B. type Ib
Which statement is true for the pathway of fine tactile sensation of the skin (Goll - Burdach)?
A. the first switching over takes place in the thalamus
B. it is constituted of four neurons
C. the first switching over takes place in the medulla oblongata
D. the first neuron is typically bipolar
C. the first switching over takes place in the medulla oblongata
Which statement is true for the dorsal spinocerebellar tract?
A. the first switching over takes place in the thalamus
B. it is identical with the Gowers’ pathway
C. the pathway bypasses the Clarke nucleus
D. its third neuron is in cerebellum
D. its third neuron is in cerebellum
Which statement is true for the lateral spinothalamic tract?
A. its second neuron is in the substantia gelatinosa Rolandi
B. It conducts unconscious informations
C. the axon of the third neuron does not leave the thalamus
D. it bypasses the Lissauer bundle
A.its second neuron is in the substantia gelatinosa Rolandi