MLSP: ISBB Flashcards

1
Q

study of immune system (prevents
the establishment if infection in the body)

A

IMMUNOLOGY

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2
Q

Study of molecules, cells, tissue, organs, and
systems whose function is to recognize and dispose
harmful substances or foreign substances

A

IMMUNOLOGY

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3
Q

Study of desirable and undesirable consequences of
the immune system

A

IMMUNOLOGY

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4
Q

study of antigen-antibody reactions,
Study of non-cellular component of the blood called
SERUM

A

SEROLOGY

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5
Q

Samples used in serological test?

A
  • Serum – most commonly used
  • CSF
  • Urine
  • Stool
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6
Q

T or F
WHEN TO USE SEROLOGY?
Unable to culture infectious agent
Confirmation of etiologic ID of the specimens
Diagnosis of immunologically-related disorders
Determine immune status

A

True

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7
Q

Also known as FOREIGN SUBSTANCES

A

ANTIGEN

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8
Q

Stimulate the immune system [once it has entered
the body]

A

ANTIGEN

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9
Q

Substances that induce or elicit an immune
response/ production of
antibodies

A

ANTIGEN

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10
Q

Also knowns as IMMUNOGLOBULINS

A

ANTIBODIES

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11
Q

One of the major substances produced by the
immune system that will block harmful antigen

A

ANTIBODIES

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12
Q

OVERVIEW OF SEROLOGICAL TEST

Antigens involved are particulate
Clumping of reactants in serological test

A

Agglutination

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13
Q

OVERVIEW OF SEROLOGICAL TEST

Antigens involved are soluble antigens
Liquid form or formation of sediments in the mixture

A

Precipitation

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14
Q

Only use for screening for syphilis, uses heated
serum
Principle; flocculation

A

VDRL – VENEREAL DISEASE RESEARCH
LABORATORY TEST

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15
Q

Also known as Enzyme immunoassay
Measures enzymatic reactions
Uses enzymes as labels

A

ELISA – ENZYME LINKED IMMUNOSORBENT ASSAY

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16
Q

Only use for screening for syphilis, uses unheated
serum
Principle: flocculation

A

RAPID PLASMA REAGIN

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17
Q

Uses fluorescent compounds known as
fluorophores or fluorochrome as labels

A

FLUORESCENT IMMUNOASSAY

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18
Q

Uses radioactive substances as label

A

RADIOIMMUNOASSAY

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19
Q

Defending the body against infections
Recognizing and responding to foreign antigens
Defending the body against the development of
tumors

A

ROLE OF THE IMMUNE SYSTEM

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20
Q

The condition of being resistant to infection
The recognition of foreign substances and
subsequent production of antibodies to these
substances

A

IMMUNITY

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21
Q

T or F
Immunity can be classified as either innate or acquired
- Innate or natural immunity
- Acquired or adaptive immunity

A

True

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22
Q

Innate or non-adaptive or non-specific
Ability of an individual to resist infections by means
of normally present body functions
Present at Birth

A

NATURAL IMMUNITY

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23
Q

Adaptive or specific – a reaction resulting from
invasion of foreign substances

A

ACQUIRED IMMUNITY

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24
Q

the source of that is an infection; being exposed then immune

A

Natural Active

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25
Q

vaccine, this is when the body is involved in producing antibodies

A

Artificial Active

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26
Q

mother’s breastmilk: maternal source

A

Natural Passive

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27
Q

commercially prepared; medical-grade; blood
donation

A

Artificial Passive

28
Q

T or F

The body is supplied with antibodies; the body
is given an already-made antibody (from an
outside source)

A

True

29
Q

Also known as Immunohematology
Refers to the collection, processing, typing and
storage of whole blood and other blood products

A

BLOOD BANKING

30
Q

Study of immunologic principles applied in blood
group specific antigen and antibodies

A

BLOOD BANKING

31
Q

It also deals with mechanism of blood typing and
crossmatching, detection and measurement of
antibody titers, screening of donors for blood
donation, bleeding techniques, proper labeling,
storing and disposal of blood emphasis on quality
assurance

A

BLOOD BANKING

32
Q

Detection of antigens on patients RBC using
known commercial anti-sera

A

Forward or Direct Typing

33
Q

Detection of antibodies in serum of patient with
known commercial RBCs suspension, and to check if the blood type of the forward is correct

A

Reverse or Back Typing

34
Q

T or F
Blood Donor Screening
Ensure the safety of the donor
Ensure the safety of the recipient

A

True

35
Q

Involves donation of blood for the use of general public. You do not have a specific patient in mind; anyone who is in need of blood can use that

A

Allogenic Donation

36
Q

Involves donation of blood use of specific patient

A

Directed Donation

37
Q

Donate blood for your own use in the future, reserved when you have a rare blood type

A

Autologous Donation

38
Q

Donate specific component of blood
- blood has several components:
plasma, RBC, WBC, platelets
- you are donating these components
separately or just one of the
components of whole blood

A

Apheresis Donation

39
Q

T or F

SIX STEPS IN DONOR SCREENING AND
COLLECTION
• Registration
• Health or Medical history
• Physical examination
• Phlebotomy [like venipuncture; testing the blood
for any blood-borne disease]
• Post-donation care
• Serological Testing of donor’s blood

A

True

40
Q

what is the average amount of blood to be transfused

A

450 ml

41
Q

average volume of blood in the body?

A

5-6 L

42
Q

how many days the fluid loss can be replenish

A

4 days

43
Q

how many days the iron loss can be replenish

A

56 days

44
Q

how many days to replace or produce or to take the
lifespan of red blood cell

A

120 days

45
Q

Minimum weight requirement in blood donation

A

50kgs/110lbs

46
Q

T or F

There should be 10.5 mL/kg to be donated

A

True

47
Q

T or F

Required temperature is not >37° or 99.5°F

A

True

48
Q

Preferred blood pressure?
Systole and Diastole

A

Systole: not <180mmHg
Diastole: not <100mmHg

49
Q

Normal Pulse rate

A

50-100 or 60-100bpm

50
Q

it is the oxygen carrying capacity of the blood

A

Hemoglobin

51
Q

it is the volume of RBC

A

Hematocrit

52
Q

Hemoglobin
Standard Method?

A

cyanmethemoglobin

53
Q

Hemoglobin Screening Test? (manual method)

A

Copper Sulfate Solution

54
Q

If the blood SINK within 15 seconds

A

ACCEPT greater than >12.5 g d/L

55
Q

If the blood FLOAT within 15 seconds

A

DEFER less than <12.5 g d/l

56
Q

blood collected before separation
into components

A

Whole Blood

57
Q

Fresh whole blood cells
- Stored: 1-6°C
- Transport: 1-10°C (place inside the ice box)

A

Whole Blood

58
Q

Stored: 1-6°C
- Transport: 1-10°C (place inside the ice box)

A

Red Blood Cells

59
Q

Stored 20-24°C (room temperature with
constant agitation)
- Important to have this constant agitation so
that the platelets will not clump

A

Platelets

60
Q

plasma that is freshly separated from whole blood)
- Stored: 1-6°C
- Transfused within 24 hours

A

Fresh Frozen Plasma

61
Q

Stores: -18°C for 1 year

A

Cryoprecipitate

62
Q

Stored: -18°C

A

Plasma and Liquid Plasma

63
Q

2 methods:
- Intermittent: 1 Vein
- Continuous: 2 Veins

Anticoagulant: Heparin

Advantages:
- Large volume of blood
- Removal of unwanted substances

A

APHERESIS

64
Q

Collection of platelets by apheresis while returning
the RBCs, WBCs, and component plasma

A

PLATELET APHERESIS

65
Q

Removal of PMNs, basophils, eosinophils for
transfusion into patients whole PMNs are
ineffective or where traditional therapy has failed

A

LEUKAPHERESIS

66
Q

Collection of blood plasma by apheresis while
returning the RBCs, WBCs, and platelet

A

PLASMAPHERESIS