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K7: urologi > metastaserad njurcancer > Flashcards

metastaserad njurcancer Flashcards

1
Q

hur stor andel är metastaser vid diagnos

A

15%

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2
Q

behandling vid metastas utifrån risk-grupp (klarcellig)

A

lågrisk
- sunitinib, pazopanib (TKI)

intermediär och högrisk
- ipilimumab + nivolumab
(checkpoint-I)

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3
Q

intermediär risk

A

vid större metastasbörda börjar man med systematisk behandling

eventuellt nefrektomi om god prognos, t.ex. liten metastasbörda (2 prickar i lungan)

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4
Q

lokala symtom

A

embolisering av njurartär för blödning och smärta

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5
Q

återfall efter kurativ behandling

A

lokal recidiv = fortsatt chans till bot, överväg kir om komplett excision möjligt, stereotaktisk strålning

fjärrmetastas = stereotaktisk strålning, kir vid enstaka metastaser, systematisk behandling

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6
Q

AK: VEGF

A

bevacizumab

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7
Q

mTOR-hämmare

A

everolimus

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8
Q

TKI

A

sunitinib
pazopanib
(VEGFR, PDGFR, c-KIT)

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9
Q

exempel vi vilka grupper av LM som kan användas

A

TKI

checkpointhämmare

mTOR-hämmare

AK

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K7: urologi (20 decks)

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