Meiosis and Recombination Flashcards
Difference between Meiosis and Mitosis
Meiosis is Diploid producing 4 haploid cells. Mitosis is diploid producing 2 diploid cells.
In Meiosis, which phase is the phase where all of the cell’s genetic material gets replicated?
S-phase of interphase. Still diploid at this point
What happens in G1 of interphase?
Protein and nucleic acid synthesis occuring
Which round of meiosis is similar to mitosis
meiosis II
Prophase I
homologous pairs line up, forming a tetrad. Allows for recombination. Longest phase, nuclear envelope disappearing. Centrioles migrate to their poles via microtubule organizing centers.
Metaphase I
Tetrads line up across the metaphase plate.
Anaphase I
Pulling apart homologous sets of chromosomes.
Telophase I and Cytokinesis
Each Chromosome actually has 2 copies of genetic info because it was replicated in Interphase. Still considered haploid. 2 haploid cells are produced
Meiosis II
Same as Meisosis I except there are no tetrads lining up and pulling apart, it is only sister chromatids. The two haploid cells produced in Meiosis I go through the phase again (similar to mitosis) and produce 4 haploid cells (mitosis produces 2 diploid cells)
Nondisjunction
Failure of tetrads to separate during meiosis I or sister chromatids in Meiosis II. Down Syndrome (trisomy 21), Turner syndrome (only X chromosome), Kleinfelters syndrome (extra X)
Nondisjunction in MI
two trisomy and two monosomy. monosomy are nonviable offspring. More troublesome than in MII
Nondisjunction in MII
1 trisomy, 1 monosomy, 2 normal.
Translocation
Movement of a Segment of one chromosome to another non-homologous chromosome (Downs Syndrome- chromosome 21 to 14)
Recombination
Adds to genetic diversity, really common. Can have single and double crossover.
Linked genes
genes on the same chromosome that probably will not undergo independent assortment. The closer together the chromosome the greater the linkage between genes. The likelihood of recombination increases with distance between genes.