Cell communication Flashcards
Fluid Mosaic Model of Plasma Membrane
Phospholipid Bilayer, Proteins, Cholesterol
Types of membrane proteins
transmembrane, integral, peripheral. Usually glycosylated
Transmembrane Protein
Channel Proteins, Spans membrane
Integral Proteins
Hydrophobic region that anchors it to the phospholipid bilayer. Usually has polysaccharides on it
Peripheral Protein
Electrostatic, Not actually anchored
Why is it important to separate inside and outside of the cell with plasma membrane?
Compartmentalization. Creates Gradients, islets nutrients
Channel Protein
Allows polar, large molecules to pass through the plasma membrane. Form barrel in membrane. Very specific
Carrier Proteins
Actually bind the thing trying to get through and cause conformational change, carries it through the membrane
Porins
Holes in membrane that all simple diffusion. Not specific, not common in animal cells
What is the significance in the membrane proteins being glycosylated?
Happens in Golgi and RER, recpetors, play role in signaling, for barriers
What gives cell receptors their recognition capabilities?
Polysaccharides. On exterior of cell receptor where the ligand binds.
Adhesion Proteins
Gap Junction, Tight Juction, Desmosomes, Plasmadesmata
Gap Junctions
Nutrient exchange, cell-to-cell communication. Example is heart
Tight Junctions
Encircle cells and adhere to cells around it. Seal extracellular space. Example is GI Tract
Desmosomes
Spot welds between cells. Mechanical strength. example is Skin
Plasmadesmata
Between plant cells. Open channels between the cells that allow nutrients to exchange
Glycocalics
Carb Coating around a cell.Not all cells have this. More common in bacteria. Barrier to infection and help in adhesion for cell to cell communication
Passive Transport
Doesn’t require ATP. With the concentration gradient. Simple and Facilitated diffusion