MATERNAL ILLNESS AND INFECTIONS DURING PREGNANCY II Flashcards
Which type of infection has caused this pathology depicted?
rubella
cytomegalovirus
group B steptococcus
syphilis
Which type of infection has caused this pathology depicted?
rubella
cytomegalovirus
group B steptococcus
syphilis
owl eyes
What is the classic triad of congenital toxoplasmosis? [3]
There is a classic triad of features in congenital toxoplasmosis:
Intracranial atherosclerosis / calcification
Hydrocephalus
Chorioretinitis (inflammation of the choroid and retina in the eye)
When is infection from T. gondii most problematic?
If woman newly infected during or just before pregnancy infection can pass to baby
More severe if infected earlier in pregnancy (1st trimester)
Diagnosis [2] and treatment of congenital toxoplasmosis? [3]
Diagnosis: PCR of amniotic fluid / maternal serology
Give prophylactic in mother:
- Pyrimethamine
- sulfadiazine
- folinic acid
HSV 1 and HSV 2 causes which type of pathologies? [2]
HSV-1: coldsores
HSV-2: genital herpes
Describe how HSV-2 infects newborn [2]
During vaginal delivery is passed from mother to baby
Common to have infection in eye / scalp
Treatment for HSV-2? [1]
Prognosis if left untreated in baby? [1]
Acyclovir
65% chance of mortality if left untreated !
At what stage during pregnancy does group B strep cause biggest risk to child? [1]
During birth [1]
Group B Steptococcus neonatal infection can cause what 4 pathological consequences? [4]
Pneumonia
Meningitis
Non-focal sepsis
Death
Why does giving treatment for group B Strep not work throughout pregnancy? [1]
When can you give? [1] What drug is used to treat? [1]
If treat during pregnancy it just returns lol
Give benzylpenicillin in labour / from week 36
Treatment for UTIs? [3]
Treatment:
Penicillin’s
Cephalosporins ( β-lactam antibiotics)
Nitrofurantoin
Which food types can listeria be found in?
Unpasterised cheeses
Uncooked meat
Wash salad and cheese
Consequences of untreated Listeria / Listeriosis? [3]
Meningo-encaphalitis
Still birth
Neonatal sepsis / meningitis
Consequences of congenital syphilis
in early years?
in late years?
Early 0-2 years
* Rash
* Rhinorrhoea (mucus full of T.pallidum)
* Osteochondritis
* Perioral fissures
* Lymphadenoapthy
* Pemphigus syphiliticus
Late >2 years
* Hutchinson’s teeth
* Clutton’s joints
* Saber shins
* High arched palate
* Deafness
* Saddle nose deformity
* Frontal bossing
Pathological consequences of chlamdyia or gonorrhoea for new born foetus? [2]
Ophthalmia neonatorum:
* Unilateral or bilateral watery discharge becomes copious and purulent
* With gonococcal infection less inflamed
Pneumonia
Which of the following is caused by chlaymdia and gonorrhoea? [1]
Right is chlamdyia
