HD1 Histology Review (Male) Flashcards

1
Q

what are the sertoli cells function? [2]

where are they located? [1]

what are nuclei like? [2]

A

what are the sertoli cells function? [1]

  • *- form blood-testis barrier:** act as a bridge between interbular space and lume of tubule
  • nourishment of spermatogenic cells

where are they located? [1]
- seminiferous tubules: span from the basement membrane to the lumen. ​

what are nuclei like? [2]
ovoid or triangular

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2
Q

label A & B of seminiferous tubule

A

A: sertoli cell
B: leydig cell

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3
Q

what is difference of nuclei between early spermatids and late spermatids? [1]

A

early: less condense
late: condensed nuclei - becomes elongated

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4
Q

where do you find leydig cells? [1]

what key feature do leydig cells normall have? [1]

A

where do you find leydig cells? [1]
outside of seminiferous tubules

what key feature do leydig cells normall have? [1]
Reinke crystals: rod shaped cytoplasmic inclusions (function unknown)

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5
Q

label A & B

A

A: Leydig cells
B: Reinke crystals

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6
Q

label a & B

A

A: testis
B: epididymis

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7
Q

which of the following is the vas deferens?

1
2
3
4
5

A

which of the following is the vas deferens?

1
2
3
4
​5

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8
Q

which of the following is the epididymis?

1
2
3
4
5

A

which of the following is the epididymis?

1
2
3
4
5

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9
Q

which of the following is the tubulus rectus?

1
2
3
4
5

A

which of the following is the tubulus rectus?

1
2
3
4
5

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10
Q

which of the following is the rete testis?

1
2
3
4
5

A

which of the following is the rete testis?

1
2
3
4
5

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11
Q

at the end of each seminfierous tubule there is a transition to straight tubules (aka WHAT)? [1]

what is the histological change that occurs here? [1]

what do the tubules empty into? [1]

A

at the end of each seminfierous tubule there is a transition to straight tubules (aka WHAT)? [1] tubuli recti

what is the histological change that occurs here?
changes to simple cuboidal epi

what do the tubules empty into? [1]
rete testis

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12
Q

what type of cells does the genital ducts become when it gets to the efferent ductules? [1]

A

what type of cells does the genital ducts become when it gets to the efferent ductules? [1]
pseudostratified columnar epi

looks saw toothed !

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13
Q

what type of cell is A? [1]

how can you tell? [1]

what is the function of A? [1]

A

what type of cell is A? [1]
leydig

how can you tell? [1]
clear cytoplasm

what is the function of A? [1]
The Leydig cells make and secrete testosterone, in response to lutenising hormone from the pituitary.

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14
Q

which part of the male reproductive system is this?

epididymis
tubulus rectus
vas deferens
efferent ductules

A

which part of the male reproductive system is this?

epididymis
tubulus rectus
vas deferens
efferent ductules: saw toothed !

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15
Q

which part of the male reproductive system is this?

epididymis
tubulus rectus
vas deferens
efferent ductules

A

which part of the male reproductive system is this?

epididymis
tubulus rectus
vas deferens
efferent ductules: saw toothed !

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16
Q

which cell types do you find in the epididymis? [3]

A

which cell types do you find in the epididymis? [3]
pseudo strat columnar epi
principal cells: have stereocilia!!
basal cells

17
Q

what is distincitve features of vas deferens?

A

pseudostratified columnar epi
tall columnar cells with long microvilli
circular and long layers smooth muscle

18
Q

seminal vesicles histology?

function?

A

high folding mucosa with primary folds folding into secondary and tertiary folds
supported by smooth muscle & LCT

function: contribute about 75% of volume of semen - including proteins like fructose

19
Q

what are the 4 anatomically distinct zones of prostate glands? [4]

A

Central zone: surrounds the ejaculatory ducts with mucosal glands. Resistant to carcinoma. Cells have larger nuclei and basophilic cytoplasm.

Peripheral zone: Surrounds central zone with branched tubuloalveolar glands. Most carcinomas arise from this zone.

Transitional zone: Surrounds the prostatic urethra with mucosal glands. In older individuals there is hyperplasia (BPH).

Periurethral zone: Contains mucosal and submucosal glands

20
Q

what are the cell types / form (squamous etc) normally found in prostate gland? [1]

A

what are the cell types / form (squamous etc) normally found in prostate gland? [1]
normally simple columnar - but can change to all other others

older men have prostatic concretions: corporoa amylacea

21
Q

what is histology of penis like?

  • what is the name of the two masses of erectile tissue? [2]
  • what is the name of the fibroelastic layer called? [1]
A
  • what is the name of the two masses of erectile tissue? [2]
    coprora cavernosa
    corpora spongiosum
  • what is the name of the fibroelastic layer called? [1]
  • *tunica albuginea**

22
Q

label 1-8 of the seminiferous tubule

A
23
Q

sperm deposition and transport:

  • where is sperm depositied in the female? [1]
  • what characterisitc of female genital tract assists sperm movement? [1]
  • how long goes sperm transport to uterus take? [1]
  • what happens to sperm during transport to uterus? [2]
A

sperm deposition and transport:

  • where is sperm depositied in the female? [1]
  • *cervical os**
  • what characterisitc of female genital tract assists sperm movement? [1]
  • *ciliated surface of cervical os**
  • how long goes sperm transport to uterus take? [1]
  • *2-7 hrs**
  • what happens to sperm during transport to uterus? [2]
    capacitation;
    sperm become hyperactive and sensitive to surrounding signals
24
Q

How is the number of cells fusing restricted?

A

Production of second messengers on sperm/egg binding triggers polyspermy blocking.

Slow block: release of calcium in a wave that occurs on fertilisation.

  • Calcium triggers **cortical granule
  • Release and activation of cell division**
25
Q

label 1-5 of blastocyst leaving the zona pellucida

A
26
Q

which of the following is the gonadal ridge?

1
2
3
4
5
6
7

A

which of the following is the gonadal ridge?

1
2
3
4
5
6
​7

27
Q

which of the following is the primordial germ cells?

1
2
3
4
5
6
7

A

which of the following is the primordial germ cells?

1
2
3
4
5
6 red dots
7

28
Q

which of the following is the primordial germ cells?

1
2
3
4
5
6
7

A

which of the following is the primordial germ cells?

1
2
3
4
5
6 red dots
7

29
Q

which of the following is the spermatids?

A
B
C
D
E
F

A

which of the following is the spermatids?

A
B
C
D
E
​F

30
Q

which of the following is the sertoli cells?

A
B
C
D
E
F

A

which of the following is the sertoli cells?

A
B
C
D
E
F

31
Q

which of the following is the 1ary spermatocytes?

A
B
C
D
E
​F

A

which of the following is the 1ary spermatocytes?

A
B
C
D
E
​F

32
Q

which of the following is the 2ary spermatocytes?

A
B
C
D
E
F

A

which of the following is the 2ary spermatocytes?

A
B
C
D
E
F

33
Q

which of the following is the spermatozoa?

A
B
C
D
E
F

A

which of the following is the spermatozoa?

A
B
C
D
E
F

34
Q

what are the the future roles of the trophoblast cells and pluriblast cells of morula? [2]

A

what are the the future roles of the trophoblast cells and pluriblast cells of morula? [2]

trophoblast cells: attach of embryo to uterus

pluriblast cells: future embryo