Markers and Disease associated Flashcards
Gene marker associated with ankylosing spondylitis
HLA-B27
Gene marker associated with multiple sclerosis
HLA-DR3
Gene marker associated with systemic lupus erythematosus (SLE)
HLA-DR2, HLA-DR3
Gene marker associated with rheumatoid arthritis (RA)
HLA-DR4
Gene markers associated with Type I diabetes mellitus
HLA-DR3, HLA-DR4
Complement deficiency associated with lupus-like syndrome and recurrent infections
C1, C2, C4
Complement deficiency associated with severe recurrent infections and glomerulonephritis
C3
Complement deficiencies associated with recurrent Neisseria infections
C5, C6, C7, C8, Properdin
Complement component linked to hereditary angioedema
C1 Inhibitor (C1-INH)
Complement regulatory protein deficiencies causing Paroxysmal Nocturnal Hemoglobinuria
DAF and/or MIRL
Deficiencies in Factor H or I result in
Recurrent pyogenic infections
Enzyme marker associated with liver cancer
Alcohol dehydrogenase, Aldolase
Enzyme marker associated with bone, liver, and leukemia-related cancers
Alkaline phosphatase
Enzyme marker associated with prostate cancer
Prostatic Acid Phosphatase
Enzyme marker associated with small cell lung cancer, neuroblastoma, and melanoma
Neuron Specific Enolase
Enzyme marker associated with lymphoma and leukemia
Lactate Dehydrogenase
Hormone marker linked to Cushing’s syndrome and lung cancer
ACTH
Hormone marker linked to lung, adrenal cortex, and pancreatic cancers
ADH
Hormone marker linked to medullary thyroid cancer
Calcitonin
Hormone marker linked to pheochromocytoma and neuroblastoma
Vasoactive Intestinal Peptide
Hormone marker linked to choriocarcinoma and embryonal cancers
Human Chorionic Gonadotropin (hCG)
Oncofetal antigen marker associated with hepatocellular and germ cell tumors
AFP
Oncofetal antigen marker associated with liver cancer
Carcinofetal ferritin
Oncofetal antigen marker associated with colorectal, gastrointestinal, lung, breast, and pancreatic cancers
CEA
