Immunogens

Question 1

Macromolecules triggering adaptive immune response, inducing antibody formation or sensitized T cells in an immunocompetent host

Answer 1

Immunogen

Question 2

Substance that reacts with antibody or sensitized T cells but may not evoke an immune response initially

Answer 2

Antigen

Question 3

Antigen-antibody reaction zone where the reaction is in equilibrium

Answer 3

Zone of equivalence

Question 4

Exact antigen binding site on the antigen

Answer 4

Epitope

Question 5

Antibody binding site on the antibody

Answer 5

Paratope

Question 6

Low molecular weight substance capable of reacting with an antibody but unable to stimulate antibody production

Answer 6

Hapten

Question 7

Property of a substance that can react with antibodies but does not stimulate antibody production

Answer 7

Antigenicity

Question 8

Immunogen: Complete antigen composed of a hapten and a carrier protein

Answer 8

Immunogen

Question 9

Ability of an immunogen to stimulate antibody production

Answer 9

Immunogenicity

Question 10

Ability of a substance to react with its corresponding antibody

Answer 10

Antigenicity

Question 11

Are all antigens immunogens?

Answer 11

No, not all antigens are immunogens; some are haptens.

Question 12

Epitope that is formed by the conformational folding of an amino acid site

Answer 12

Discontinuous epitope

Question 13

Size requirement for an immunogen to stimulate antibody production

Answer 13

> 10,000 daltons

Question 14

Best type of immunogen

Answer 14

Proteins (more immunogenic) and polysaccharides

Question 15

Less immunogenic substance

Answer 15

Carbohydrates

Question 16

Substance not immunogenic and acts as a hapten

Answer 16

Nucleic acids and lipids

Question 17

Term for antigen derived from the same individual

Answer 17

Autoantigen

Question 18

Term for antigen derived from a different individual of the same species

Answer 18

Alloantigen

Question 19

Term for antigen derived from a different species

Answer 19

Xenogenic

Question 20

Antigen found in unrelated plants and animals that cross-react with other antibodies

Answer 20

Heterophile

Question 21

Term for a transplant of tissue from the same individual

Answer 21

Autograft

Question 22

Term for a transplant from an identical individual (e.g., identical twins)

Answer 22

Isograft

Question 23

Term for a transplant from a different individual but the same species

Answer 23

Allograft

Question 24

Term for a transplant from a different species

Answer 24

Heterograft/Xenograft

Question 25

Greatest immune response is observed from a transplant of this organ

Answer 25

Animal transplant (Pig’s heart)