Graft rejection

Question 1

Phase of rejection with preexisting antibodies and complement activation

Answer 1

Hyperacute rejection

Question 2

Phase of rejection involving CD4, CD8, NK cells, and macrophages

Answer 2

Acute rejection

Question 3

Phase of rejection with slow, progressive renal failure

Answer 3

Chronic rejection

Question 4

Test for matching HLA antigens between donor and recipient

Answer 4

Tissue typing

Question 5

Test for presence of preformed antibodies to donor HLA

Answer 5

Screening for preformed antibodies

Question 6

Test to detect immune reaction between donor and recipient cells

Answer 6

Crossmatching

Question 7

Type of graft most sensitive to rejection

Answer 7

Bone marrow and skin grafts

Question 8

Rejection type with no therapy for prevention or termination

Answer 8

Hyperacute rejection

Question 9

Rejection involving T cell-mediated attack on host MHC

Answer 9

Graft-versus-host disease (GVHD)

Question 10

Time frame for acute rejection

Answer 10

10-30 days

Question 11

Time frame for chronic rejection

Answer 11

Months to years

Question 12

Rejection with rapid kidney function loss

Answer 12

Acute rejection

Question 13

Rejection with complement activation and platelet deposition

Answer 13

Hyperacute rejection

Question 14

Phase of rejection with mixed humoral and cellular mechanisms

Answer 14

Chronic rejection

Question 15

Phase of rejection occurring in days

Answer 15

Accelerated rejection

Question 16

Laboratory test for detecting HLA mismatch

Answer 16

Lymphocytotoxicity test

Question 17

Test to measure direct allorecognition

Answer 17

Mixed lymphocyte reaction

Question 18

Mitomycin C-treated or irradiated donor lymphocytes + live recipient lymphocytes

Answer 18

Increase in proliferation of recipient lymphocytes

Question 19

Ability to distinguish own tissues from those of another

Answer 19

allorecognition