Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IMMUNOSEROLOGY > Cytokines > Flashcards

Cytokines Flashcards

1
Q

Generic term for soluble mediators that regulate the immune system

A

Cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Function of interleukins in the immune system

A

Immune cell differentiation and activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Example of an interleukin that acts as an endogenous pyrogen

A

IL-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Example of an interleukin that acts as a T cell growth factor

A

IL-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Effect of IL-2 on immune cells

A

Growth and differentiation of B and T cells, induces lytic activity of NK cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Effect of IL-6 on immune cells

A

Stimulates B-cells to become plasma cells, induces CD4+ cells to produce cytokines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Effect of IL-4 in the immune system

A

Regulates Th2 immune activities, drives antibody response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Effect of IL-10 on the immune system

A

Inhibitory effect on the immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Proteins produced by virally infected cells to protect neighboring cells

A

Interferons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anti-viral activity of interferons

A

Virus-nonspecific but host-specific anti-viral activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Types of interferons

A

Type 1 (Alpha and Beta), Type 2 (Gamma)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Type of interferon produced by leukocytes and Null cells/NK cells

A

Interferon Alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Type of interferon produced by fibroblasts and epithelial cells

A

Interferon Beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Function of Type 1 interferon

A

Non-immune, product of the initial response to viral infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Type of interferon that is part of the specific immune response to pathogens

A

Interferon Gamma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Major producers of Interferon Gamma

A

Th1 cells

17
Q

Function of Tumor Necrosis Factor (TNF)

A

Cytotoxic activity against tumor cells and virally infected cells

18
Q

Produced by macrophages and known as cachectin

A

TNF Alpha

19
Q

Produced by CD4 and CD8 cells and known as lymphotoxin

A

TNF Beta

20
Q

Function of chemokines

A

Enhances motility and promotes migration of white blood cells

21
Q

Substance released by platelets during coagulation that affects gram-positive bacteria

A

Betalysin

22
Q

Function of Transforming Growth Factor-B

A

Induces antiproliferative activity and helps downregulate inflammatory response

IMMUNOSEROLOGY (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions