Magnesium Sulfate

Question 1

Magnesium Sulfate Trade Name?

Answer 1

Magnesium Sulfate

Question 2

Magnesium Sulfate Classification?

Answer 2

Class V Anti-Dysrhythmic, Mineral, electrolyte

Question 3

Magnesium Sulfate Mechanism?

Answer 3

Competes with with calcium at NMJ to affect distribution of calcium uptake and release. Decreases amount of Ach released at motor end plate and slows SA node impulses and conduction time

Question 4

Magnesium Sulfate Indications?

Answer 4

• Severe bronchospasm associated with asthma and COPD
• Torsades de Pointes
• Eclamptic seizures
• Hypomagnesemia
• VF/VT arrest refractory to amiodarone
• Dysrhythmia due to digitalis toxicity

Question 5

Magnesium Sulfate Contraindications?

Answer 5

• Heart block
• Persistent hypertension
• Dialysis patients
• Hypocalcemia

Question 6

Magnesium Sulfate Side Effects/Precautions?

Answer 6

• NS depression
• Respiratory depression
• Paralysis
• Bradycardia
• Burning at injection site
• Decreased reflexes
• Nausea/vomiting
• Hypotension
• Vasodilation
• Itching/rash

Question 7

Magnesium Sulfate Adult Dose?

Answer 7

Adult:
Cardiac: 1 g over 1 minute IV/IO
Respiratory: 2 g in 100 ml of NS over 10 minutes IV/IO
Eclampsia: 4g in 100 ml over 5-10 minutes IV/IO

Peds: 25-50 mg/kg in 100 ml over 10 minutes
Max-Adults(Peds): 10g/day(2g/day)

Question 8

Magnesium Sulfate Pediatric Dose?

Answer 8

25-50 mg/kg in 100 ml over 10 minutes; max 2 g

Question 9

Magnesium Sulfate Onset of Action?

Answer 9

Immediate

Question 10

Magnesium Sulfate Duration of Action?

Answer 10

Variable

Question 11

Magnesium Sulfate Max Dose Adult/Pediatric?

Answer 11

Adult 10g/day. Peds 2g/day

Question 12

Magnesium Sulfate Routes of Administration?

Answer 12

IV/IO

Question 13

Magnesium Sulfate How Supplied?

Answer 13

500mg/ml vials (50% solution)